Imperial College London


Faculty of MedicineDepartment of Brain Sciences

Lead for In vivo Neurobiology



m.kopanitsa Website




Burlington DanesHammersmith Campus





Maksym V. Kopanitsa was born and educated in Ukraine. He graduated from the Odessa State University and received his PhD in Biophysics at the Bogomoletz Institute of Physiology (Kyiv, Ukraine), where he carried out research on pharmacology of voltage- and ligand-gated ion channels and synaptic transmission. During his post-doctoral appointments at the University of Dundee (2003–2004) and the Wellcome Trust Sanger Institute in Cambridge, UK (2004–2010), Maksym worked with genetically altered mice to study genetic regulation of synaptic transmission in brain slices.

In 2010–2018, Maksym Kopanitsa held industrial positions at preclinical CROs Synome Ltd (Cambridge, UK) and Charles River Discovery (Kuopio, Finland). In his capacity of Chief Operating Officer (Synome) and Head of Translational Biology (Charles River), Maksym supervised studies of rodent brain slice electrophysiology and behaviour in a wide range of neurodegenerative disease models for industrial clients and academic collaborations within several EU FP7 consortia.

In 2018, Maksym joined the UK Dementia Research Institute (DRI) at Imperial College London where he will collaborate with DRI fellows in the application of their fundamental research discoveries to preclinical models of neurodegenerative conditions.

Selected Publications

Journal Articles

Kopanitsa M, Lehtimaki KK, Forsman M, et al., 2020, Cognitive disturbances in the cuprizone model of multiple sclerosis, Genes, Brain and Behavior, ISSN:1601-183X

Zhu F, Cizeron M, Qiu Z, et al., 2019, Architecture of the mouse brain synaptome, Neuron, Vol:99, ISSN:0896-6273, Pages:781-799.e10

Piiponniemi TO, Parkkari T, Heikkinen T, et al., 2018, Impaired performance of the Q175 mouse model of Huntington’s disease in the touch screen paired associates learning task, Frontiers in Behavioral Neuroscience, Vol:12, ISSN:1662-5153

Horner AE, McLaughlin CL, Afinowi NO, et al., 2018, Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95, European Journal of Neuroscience, Vol:47, ISSN:0953-816X, Pages:164-176

Fernandez E, Collins MO, Frank RAW, et al., 2017, Arc requires PSD95 for assembly into postsynaptic complexes involved with neural dysfunction and intelligence, Cell Reports, Vol:21, ISSN:2211-1247, Pages:679-691

Arbogast T, Iacono G, Chevalier C, et al., 2017, Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition, PLOS Genetics, Vol:13, ISSN:1553-7390

Piiponniemi TO, Bragge T, Vauhkonen EE, et al., 2017, Acquisition and reversal of visual discrimination learning in APPSwDI/Nos2-/-(CVN) mice., Neuroscience Letters, Vol:650, ISSN:0304-3940, Pages:126-133

Arbogast T, Ouagazzal A-M, Chevalier C, et al., 2016, Reciprocal effects on neurocognitive and metabolic phenotypes in mouse models of 16p11.2 deletion and duplication syndromes, PLOS Genetics, Vol:12, ISSN:1553-7390

Ryan TJ, Kopanitsa MV, Indersmitten T, et al., 2013, Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior., Nat Neurosci, Vol:16, Pages:25-32

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