Imperial College London

Professor Marina Kuimova

Faculty of Natural SciencesDepartment of Chemistry

Professor of Chemical Physics
 
 
 
//

Contact

 

+44 (0)20 7594 8558m.kuimova

 
 
//

Location

 

207BMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Robson:2020:10.1002/anie.202008224,
author = {Robson, J and Kubankova, M and Bond, T and Hendley, R and White, A and Kuimova, M and Wilton-Ely, J},
doi = {10.1002/anie.202008224},
journal = {Angewandte Chemie International Edition},
pages = {21431--21435},
title = {Simultaneous detection of carbon monoxide and viscosity changes in cells},
url = {http://dx.doi.org/10.1002/anie.202008224},
volume = {59},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A new family of robust, nontoxic, watercompatible ruthenium(II) vinyl probes allows the rapid, selective and sensitive detection of endogenous carbon monoxide (CO) in live mammalian cells under normoxic and hypoxic conditions. Uniquely, these probes incorporate a viscositysensitive BODIPY fluorophore that allows the measurement of microscopic viscosity in live cells via Fluorescence Lifetime Imaging Microscopy (FLIM) in conjunction with measuring CO. This is the first example of a probe that can simultaneously detect CO alongside small viscosity changes in organelles of live cells.
AU - Robson,J
AU - Kubankova,M
AU - Bond,T
AU - Hendley,R
AU - White,A
AU - Kuimova,M
AU - Wilton-Ely,J
DO - 10.1002/anie.202008224
EP - 21435
PY - 2020///
SN - 1433-7851
SP - 21431
TI - Simultaneous detection of carbon monoxide and viscosity changes in cells
T2 - Angewandte Chemie International Edition
UR - http://dx.doi.org/10.1002/anie.202008224
UR - https://onlinelibrary.wiley.com/doi/10.1002/anie.202008224
UR - http://hdl.handle.net/10044/1/81450
VL - 59
ER -