Publications
243 results found
Stasinou S, Valasoulis G, Kyrgiou M, et al., 2013, LONG-TERM DATA ON THE TREND OF HPV-RELATED BIOMARKERS POST-TREATMENT FOR CIN, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 23, ISSN: 1048-891X
Gajjar K, Valasoulis G, Founta C, et al., 2013, BIOSPECTROSCOPY OF CERVICAL CYTOLOGY VS. CONVENTIONAL SCREENING IN IDENTIFICATION OF HISTOLOGY VERIFIED CERVICAL INTRA-EPITHELIAL LESIONS, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 23, ISSN: 1048-891X
Kyrgiou M, Pugh R, Hird V, et al., 2013, FERTILITY-SPARING TREATMENT FOR YOUNG WOMEN WITH ATYPICAL HYPERPLASIA AND EARLY ENDOMETRIAL CANCERWITH HIGH-DOSE MEDROXYPROGESTERONE ACETATE, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 23, ISSN: 1048-891X
Kyrgiou M, Warwick JANE, Swart A, et al., 2013, LAPAROSCOPIC VERSUS OPEN HYSTERECTOMY FOR EARLY STAGE ENDOMETRIAL CANCER: RESULTS FROM THE MRC ASTEC TRIAL, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 23, ISSN: 1048-891X
Stasinou S, Paraskevaidis E, Valasoulis G, et al., 2013, THE ALTERATIONS OF HPV-RELATED BIOMARKERS AND THE USEFULNESS ROLE OF SCORING SYSTEM FOR THE SURVEILLANCE OF CERVICAL PATHOLOGY DURING PREGNANCY: PRELIMINARY RESULTS, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 23, ISSN: 1048-891X
Kyrgiou M, Taher SE, Shennan A, et al., 2013, Cervical-Length Indicated Cervical Cerclage Versus Routine Antenatal Care after Treatment for Cervical Precancer, 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI), Publisher: SAGE PUBLICATIONS INC, Pages: 122A-123A, ISSN: 1933-7191
Kyrgiou M, Founta C, Valasoulis G, et al., 2013, Proportion of Excision, Cervical Healing and Pregnancy Outcomes after Large Loop Excision of the Transformation Zone for Cervical Intraepithelial Neoplasia., 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI), Publisher: SAGE PUBLICATIONS INC, Pages: 273A-273A, ISSN: 1933-7191
Kyrgiou M, Warwick J, Swart AM, et al., 2013, Laparoscopic Versus Open Hysterectomy for Endometrial Cancer: The ASTEC Trial., 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI), Publisher: SAGE PUBLICATIONS INC, Pages: 339A-339A, ISSN: 1933-7191
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- Citations: 2
Kyrgiou M, Papakonstantinou K, Valasoulis G, et al., 2013, Untreated High-Grade Cervical Intra-Epithelial Lesions: Is There a Role for the Use of HPV-Related Biomarkers?, 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI), Publisher: SAGE PUBLICATIONS INC, Pages: 273A-273A, ISSN: 1933-7191
Vitoratos N, Vrachnis N, Iavazzo C, et al., 2012, Preeclampsia: Molecular mechanisms, predisposition, and treatment, Journal of Pregnancy, Vol: 2012, ISSN: 2090-2735
Kyrgiou M, Arbyn M, Martin-Hirsch P, et al., 2012, Increased risk of preterm birth after treatment for CIN, BRITISH MEDICAL JOURNAL, Vol: 345, ISSN: 1756-1833
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- Citations: 43
Soutter WP, Moss B, Perryman K, et al., 2012, Long-term compliance with follow-up after treatment for cervical intra-epithelial neoplasia, ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, Vol: 91, Pages: 1103-1108, ISSN: 0001-6349
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- Citations: 14
Stasinou SM, Valasoulis G, Kyrgiou M, et al., 2012, Large Loop Excision of the Transformation Zone and Cervical Intraepithelial Neoplasia: A 22-Year Experience, ANTICANCER RESEARCH, Vol: 32, Pages: 4141-4145, ISSN: 0250-7005
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- Citations: 17
Woo YL, Kyrgiou M, Bryant A, et al., 2012, Centralisation of services for gynaecological cancers - A Cochrane systematic review, GYNECOLOGIC ONCOLOGY, Vol: 126, Pages: 286-290, ISSN: 0090-8258
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- Citations: 79
Karakitsos P, Chrelias C, Pouliakis A, et al., 2012, Identification of women for referral to colposcopy by neural networks: A preliminary study based on LBC and molecular biomarkers, Journal of Biomedicine and Biotechnology, Vol: 2012, ISSN: 1110-7251
Objective of this study is to investigate the potential of the learning vector quantizer neural network (LVQ-NN) classifier on various diagnostic variables used in the modern cytopathology laboratory and to build an algorithm that may facilitate the classification of individual cases. From all women included in the study, a liquid-based cytology sample was obtained; this was tested via HPV DNA test, E6/E7 HPV mRNA test, and p16 immunostaining. The data were classified by the LVQ-NN into two groups: CIN-2 or worse and CIN-1 or less. Half of the cases were used to train the LVQ-NN; the remaining cases (test set) were used for validation. Out of the 1258 cases, cytology identified correctly 72.90% of the CIN-2 or worst cases and 97.37% of the CIN-1 or less cases, with overall accuracy 94.36%. The application of the LVQ-NN on the test set allowed correct classification for 84.62% of the cases with CIN-2 or worse and 97.64% of the cases with CIN-1 or less, with overall accuracy of 96.03%. The use of the LVQ-NN with cytology and the proposed biomarkers improves significantly the correct classification of cervical precancerous lesions and/or cancer and may facilitate diagnosis and patient management.
Kyrgiou M, Stasinou SM, Arbyn M, et al., 2012, Management of low-grade squamous intra-epithelial lesions of the uterine cervix: Repeat cytology versus immediate referral to colposcopy, Cochrane Database of Systematic Reviews, Vol: 2012
This is the protocol for a review and there is no abstract. The objectives are as follows: The aim of this review will be to assess whether women with low-grade squamous intra-epithelial lesions (LSILs) should be referred immediately to colposcopy or have repeat cytology.
Khalid S, Dimitriou E, Conroy R, et al., 2012, The thickness and volume of LLETZ specimens can predict the relative risk of pregnancy-related morbidity, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 119, Pages: 685-691, ISSN: 1470-0328
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- Citations: 85
Woo YL, Kyrgiou M, Bryant A, et al., 2012, Centralisation of services for gynaecological cancer, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X
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- Citations: 55
Phadnis SV, Atilade A, Bowring J, et al., 2011, Regeneration of cervix after excisional treatment for cervical intraepithelial neoplasia: a study of collagen distribution, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 118, Pages: 1585-1591, ISSN: 1470-0328
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- Citations: 23
Lavery S, Ng C, Kyrgiou M, et al., 2011, Gestational surrogacy after intra-operative oocyte collection in a hysterectomised woman diagnosed with endometrial cancer, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 118, Pages: 1669-1671, ISSN: 1470-0328
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- Citations: 3
Kyrgiou M, Shafi MI, 2011, Laparoendoscopic single-site surgery (LESS), Obstetrics, Gynaecology and Reproductive Medicine, Vol: 21, Pages: 297-298, ISSN: 1751-7214
Tsiodras S, Hatzakis A, Spathis A, et al., 2011, Molecular epidemiology of HPV infection using a clinical array methodology in 2952 women in Greece, CLINICAL MICROBIOLOGY AND INFECTION, Vol: 17, Pages: 1185-1188, ISSN: 1198-743X
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- Citations: 8
Karakitsos P, Pouliakis A, Meristoudis C, et al., 2011, A Preliminary Study of the Potential of Tree Classifiers in Triage of High-Grade Squamous Intraepithelial Lesions, ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY, Vol: 33, Pages: 132-140, ISSN: 0884-6812
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- Citations: 21
Tsoumpou I, Valasoulis G, Founta C, et al., 2011, High-risk human papillomavirus DNA test and p16<SUP>INK4a</SUP> in the triage of LSIL: A prospective diagnostic study, GYNECOLOGIC ONCOLOGY, Vol: 121, Pages: 49-53, ISSN: 0090-8258
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- Citations: 29
Valasoulis G, Koliopoulos G, Founta C, et al., 2011, Alterations in human papillomavirus-related biomarkers after treatment of cervical intraepithelial neoplasia, GYNECOLOGIC ONCOLOGY, Vol: 121, Pages: 43-48, ISSN: 0090-8258
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- Citations: 25
Nasioutziki M, Daniilidis A, Dinas K, et al., 2011, The Evaluation of p16ink4a Immunoexpression/Immunostaining and Human Papillomavirus DNA Test in Cervical Liquid-Based Cytological Samples, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 21, Pages: 79-85, ISSN: 1048-891X
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- Citations: 28
Valasoulis G, Tsoumpou I, Founta C, et al., 2011, The role of p16<SUP>INK4a</SUP> immunostaining in the risk assessment of women with LSIL cytology: a prospective pragmatic study, EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, Vol: 32, Pages: 150-152, ISSN: 0392-2936
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- Citations: 14
Founta C, Arbyn M, Valasoulis G, et al., 2010, Proportion of excision and cervical healing after large loop excision of the transformation zone for cervical intraepithelial neoplasia, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 117, Pages: 1468-1474, ISSN: 1470-0328
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- Citations: 45
Salanti G, Dias S, Welton NJ, et al., 2010, Evaluating novel agent effects in multiple-treatments meta-regression, STATISTICS IN MEDICINE, Vol: 29, Pages: 2369-2383, ISSN: 0277-6715
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- Citations: 67
Kyrgiou M, Arbyn M, Koliopoulos G, et al., 2010, Obstetric outcomes and fertility after conservative treatment for cervical intraepithelial lesions, Cochrane Database of Systematic Reviews, Vol: 2010
This is the protocol for a review and there is no abstract. The objectives are as follows: To investigate the effect of CKC, LLETZ, LA, LC, CT, CC and RD for treating CIN and microinvasive cervical cancer on subsequent fertility and pregnancy outcomes. Furthermore, the association of prematurity with regards to the dimensions of the excised tissue will be assessed.
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