Imperial College London
Portrait Picture

Professor Maria Kyrgiou

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Chair in Gynaecologic Oncology
 
 
 
//

Contact

 

+44 (0)20 7594 2177m.kyrgiou Website

 
 
//

Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Paraskevaidis:2020:10.21873/invivo.11927,
author = {Paraskevaidis, E and Athanasiou, A and Paraskevaidi, M and Bilirakis, E and Galazios, G and Kontomanolis, E and Dinas, K and Loufopoulos, A and Nasioutziki, M and Kalogiannidis, I and Athanasiadis, A and Papanikolaou, A and Vatopoulou, A and Grimbizis, G and Tsolakidis, D and Daponte, A and Valasoulis, G and Gritzeli, S and Michail, G and Adonakis, G and Paschopoulos, M and Tsonis, O and Anaforidou, M-E and Batistatou, A and Kyrgiou, M},
doi = {10.21873/invivo.11927},
journal = {In Vivo: international journal of experimental and clinical pathophysiology and drug research},
pages = {1445--1449},
title = {Cervical pathology following HPV vaccination in Greece: A 10-year HeCPA observational cohort study},
url = {http://dx.doi.org/10.21873/invivo.11927},
volume = {34},
year = {2020}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: In Greece the population-level impact of HPV vaccination is unknown due to lacking official registries. This study presents in a pragmatic frame the comparison of cervical pathology data between HPV-vaccinated and unvaccinated women referred for colposcopy.Materials and Methods: This is an observational prospective cohort study performed in 7 academic Obstetrics & Gynaecology departments across Greece between 2009-2019. Cases were women that had completed HPV vaccination before coitarche and were referred for colposcopy due to abnormal cytology. For each vaccinated woman an unvaccinated matched control was selected. Results: A total of 849 women who had been vaccinated before coitarche and 849 unvaccinated controls were recruited. The combination of cytological, colposcopic and molecular findings necessitated treatment in only a single case among vaccinated (0.1%) and in 8.4% among unvaccinated. Conclusion: Despite potential bias, this study’s message is clear: HPV vaccination at a proper age can markedly reduce development of severe cervical precancer and consequently, the need for treatments with their long-term related obstetrical morbidity.
AU  - Paraskevaidis,E
AU  - Athanasiou,A
AU  - Paraskevaidi,M
AU  - Bilirakis,E
AU  - Galazios,G
AU  - Kontomanolis,E
AU  - Dinas,K
AU  - Loufopoulos,A
AU  - Nasioutziki,M
AU  - Kalogiannidis,I
AU  - Athanasiadis,A
AU  - Papanikolaou,A
AU  - Vatopoulou,A
AU  - Grimbizis,G
AU  - Tsolakidis,D
AU  - Daponte,A
AU  - Valasoulis,G
AU  - Gritzeli,S
AU  - Michail,G
AU  - Adonakis,G
AU  - Paschopoulos,M
AU  - Tsonis,O
AU  - Anaforidou,M-E
AU  - Batistatou,A
AU  - Kyrgiou,M
DO  - 10.21873/invivo.11927
EP  - 1449
PY  - 2020///
SN  - 0258-851X
SP  - 1445
TI  - Cervical pathology following HPV vaccination in Greece: A 10-year HeCPA observational cohort study
T2  - In Vivo: international journal of experimental and clinical pathophysiology and drug research
UR  - http://dx.doi.org/10.21873/invivo.11927
UR  - http://iv.iiarjournals.org/content/34/3/1445
UR  - http://hdl.handle.net/10044/1/78250
VL  - 34
ER  -
Download