Imperial College London
Portrait Picture

Professor Maria Kyrgiou

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Chair in Gynaecologic Oncology
 
 
 
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Contact

 

+44 (0)20 7594 2177m.kyrgiou Website

 
 
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Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{J:2020:10.1016/j.ogrm.2020.02.003,
author = {J, Bowden S and Kyrgiou, M},
doi = {10.1016/j.ogrm.2020.02.003},
journal = {Obstetrics, Gynaecology & Reproductive Medicine},
pages = {109--118},
title = {Human papillomavirus},
url = {http://dx.doi.org/10.1016/j.ogrm.2020.02.003},
volume = {30},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Human papillomaviruses are ancient small DNA viruses and represent the most common sexually transmitted infection in the world. In the majority, HPV infection is cleared by an incompletely understood immune response. HPV is a necessary but not sufficient cause of cervical cancer, and responsible for a proportion of other anogenital cancers including vulval, vaginal, anal and oropharyngeal. Oncogenesis is likely mediated through viral proteins which hijack host-cell machinery in epithelial keratinocytes and disrupt host tumour-suppressor proteins. Much work has been undertaken to further characterise the natural history of HPV infection and cervical disease. Such efforts have been translated to important public health interventions like the introduction of HPV tests in cervical screening. HPV vaccination programmes are expected to further reduce the incidence of high-risk HPV infections and resultantly HPV-related disease.
AU  - J,Bowden S
AU  - Kyrgiou,M
DO  - 10.1016/j.ogrm.2020.02.003
EP  - 118
PY  - 2020///
SN  - 1751-7214
SP  - 109
TI  - Human papillomavirus
T2  - Obstetrics, Gynaecology & Reproductive Medicine
UR  - http://dx.doi.org/10.1016/j.ogrm.2020.02.003
UR  - https://www.sciencedirect.com/science/article/pii/S1751721420300166?via%3Dihub
VL  - 30
ER  -
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