Imperial College London

Professor Maria Kyrgiou

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Clinical Professor of Gynaecological Oncology



+44 (0)20 7594 2177m.kyrgiou Website




Institute of Reproductive and Developmental BiologyHammersmith Campus





The primary focus of her research is traslational research in gynaecological diseases and cancers, in particular cervical, endometrial and ovarian cancer with an emphasis on prevention and personalised treatment.

She has an interest in cervical pre-invasive and invasive disease, primary cervical screening and HPV vaccines. She has led research into the impact of treatment for cervical pre-invasive and early invasive cervical disease on reproductive outcomes and the clinical use of HPV biomarkers in personalising the management of women with abnormal findings at primary population-based screening.

She runs a research group investigating the impact of obesity and metabolic disorders in the development of gynaecological cancers with an emphasis on endometrial cancer.

She further investigates the role of the genital tract and gut microbiome and host interactions in the development and treatment response of gynaecological cancers.

Guest Lectures

Vaginal microbiome, HPV infection & CIN, European Microbiome Congress, 2017

The Impact of Healthy Life style & Obesity on Prevention of Gynaecological Cancers, ESGO, 2017

Treatment Cervical Disease and Reproductive Outcomes, ESGO, 2017

The vaginal microbiota, HPV infection & CIN, European Conference of Pathology, 2017

Conservative Management of CIN2, BSCCP, 2017

9-valent HPV vaccine, British Society of Gynaecological Cancer, 2016

Vaccination for cervical cancer prevention: an update, 13th Panhellenic Conference of Obstetrics and Gynaecology, Volos, 2015

Challenges in the management of cervical cancer and percancer, 13th Panhellenic Conference of Obstetrics and Gynaecology, Volos, 2015

Treating recurrent CIN while preserving fertility, XII International Workshop of Lower Genital Tract Pathology, Rome, Italy, 2015

The use of HPV molecular markers in clinical applications, XII International Workshop of Lower Genital Tract Pathology, Rome, Italy, 2015

Personalised management of women with cervical disease, International meeting of the MSRM, Crete, 2014

Prevention of cervical disease in young women, 9th International Congress Women's Health and Disease, Athens, Greece, 2014

Management of stage 1B1 cervical cancer, British Gynaecological Cancer Society Meeting, London, 2014

Reproductive morbidity after cervical treatment, 48th Canadian Congress Obstetrics & Gynaecology, Montreal, Canada, 2014

Reproductive morbidity after treatment of cervical pre-invasive and early invasive disease, 15th World IFCPC Congress (International Federation of Colposcopy and Cervical Pathology), London, 2014

Adverse obstetrical effects associated with cervical treatment for cervical precancer and cancer: need for research, European Federation of Colposcopy, Prague, 2013

Management of endometrial cancer: the value of surgical staging with lymphadenectomy and medical non surgical treatment, Hellenic Conference of Gynaecologic Oncology, Athens, 2013

Debate: Excisional treatment should be abandoned, Scottish Colposcopy Meeting, Edinburgh, 2011

Treatment of CIN: how to determine reproductive and oncological safety ranges?, European Federation of Colposcopy, Berlin, 2010

When to perform an HPV testing?, College National Des Gynecologues et Obstetriciens Francais, Paris, France, 2008

Research Student Supervision

Kalliala,I, Reproductve morbidity associated with cervical disease: genome wide associations in women with cervical pre-invasive/invasive disease and preterm birth

Lever,S, Genetic and epigenetic determinants of cervical pre-invasive disease and prediction of progression

Mitra,A, The role of cervical immunity and micro biome/metabonome in cervical carcinogenesis and risk of adverse reproductive outcomes after treatment

Raglan,O, Obesity and metabolic disorders in endometrial cancer

Semerzidou,A, Genital Tract Microbiome and Host Interactions in Endometrial Cancer

Tzafettas,M, Improvement of fertility-sparing treatment for cervical disease with innovative spectroscopy techniques

Whelan,E, Genital Tract Microbiome and Host Interactions in Ovarian Cancer