Imperial College London
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ProfessorMaudLemoine

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor and Honorary Consultant in Hepatology
 
 
 
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Contact

 

+44 (0)20 3312 5212m.lemoine

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sonderup:2020:10.1111/jvh.13247,
author = {Sonderup, MW and Dusheiko, G and Desalegn, H and Lemoine, M and Tzeuton, C and Taylor-Robinson, SD and Spearman, CW},
doi = {10.1111/jvh.13247},
journal = {Journal of Viral Hepatitis},
pages = {560--567},
title = {Hepatitis B in sub-Saharan Africa-How many patients need therapy?},
url = {http://dx.doi.org/10.1111/jvh.13247},
volume = {27},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Hepatitis B is endemic in subSaharan Africa with ~60 million people chronically infected. While prevention, through vaccination, is central to elimination strategies, only 11 countries have birth dose vaccination and full vaccine coverage remains at suboptimal levels. Furthermore, to fully realize elimination, those chronically infected need to be identified, assessed for therapy and then linked to care. Given current treatment criteria, the precise quantum of people warranting therapy, according to criteria, is essentially unknown. The issue is further complicated by data to suggest differences in the numbers of people requiring treatment when applying WHO as compared to European Association for the Study of the Liver, EASL, criteria. Optimal determination of treatment eligibility is further hindered by the lack of available tools to adequately assess individual patients. It is conceivable that accurately determining the number of those requiring treatment, given the heterogeneity of hepatitis B in Africa, is difficult. Better studies and data are required. More signifcantly, improved access and availability to the diagnostic tools needed to assess patients in additon to access to drugs are as, if not more important, to achieve elimination.
AU  - Sonderup,MW
AU  - Dusheiko,G
AU  - Desalegn,H
AU  - Lemoine,M
AU  - Tzeuton,C
AU  - Taylor-Robinson,SD
AU  - Spearman,CW
DO  - 10.1111/jvh.13247
EP  - 567
PY  - 2020///
SN  - 1345-2533
SP  - 560
TI  - Hepatitis B in sub-Saharan Africa-How many patients need therapy?
T2  - Journal of Viral Hepatitis
UR  - http://dx.doi.org/10.1111/jvh.13247
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000503824800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/jvh.13247
UR  - http://hdl.handle.net/10044/1/84578
VL  - 27
ER  -
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