Imperial College London

ProfessorMichaelLevin

Faculty of MedicineDepartment of Infectious Disease

Chair in Paediatrics & International Child Health
 
 
 
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Contact

 

+44 (0)20 7594 3760m.levin Website

 
 
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Location

 

233Medical SchoolSt Mary's Campus

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Summary

 

Summary

Michael Levin MBE PhD FRCPCH FMedSci is Professor of Paediatrics and International Child Health at Imperial College London. He works as a paediatric infectious diseases consultant and has led research focused on the diagnosis and treatment of a range of childhood infections including meningococcal disease, tuberculosis, bacterial sepsis and Kawasaki disease. He currently leads the EU funded PERFORM study investigating the application of RNA transcriptomics to improve diagnosis of childhood infection. He also leads the NIH funded study Validation of Biomarkers of Pediatric TB and further development for use in diagnosis of childhood TB.

He has recently been awarded €22.5 million EU funding to develop a rapid test for serious illnesses – the DIAMONDS project (Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis).

Pofessor Levin received an MBE for his services to infectious diseases, critical care and research in paediatrics in the Queen's New Year's honour list in 2017.

 

Selected Publications

Journal Articles

Martinón-Torres F, Salas A, Rivero-Calle I, et al., 2018, Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study, Lancet Child and Adolescent Health, Vol:2, ISSN:2352-4642, Pages:404-414

Boeddha NP, Schlapbach LJ, Driessen GJ, et al., 2018, Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS), Critical Care, Vol:22, ISSN:1364-8535

von Both U, Berk M, Agapow P-M, et al., 2018, Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival, Scientific Reports, Vol:8, ISSN:2045-2322

Kaforou M, Herberg JA, Wright VJ, et al., 2017, Diagnosis of bacterial infection using a 2-transcript host RNA signature in febrile infants 60 days or younger, JAMA - Journal of the American Medical Association, Vol:317, ISSN:0098-7484, Pages:1577-1578

Herberg JA, Kaforou M, Wright VJ, et al., 2016, Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children, Journal of the American Medical Association, Vol:316, ISSN:0002-9955, Pages:835-845

Kaforou M, Wright VJ, Levin M, 2014, Host RNA signatures for diagnostics: An example from paediatric tuberculosis in Africa, Journal of Infection, Vol:69, ISSN:0163-4453, Pages:S28-S31

Anderson ST, Kaforou M, Brent AJ, et al., 2014, Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa, New England Journal of Medicine, Vol:370, ISSN:1533-4406, Pages:1712-1723

Eleftherohorinou H, Hoggart CJ, Wright VJ, et al., 2011, Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways, Human Molecular Genetics, Vol:20, Pages:3494-3506

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