Imperial College London
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ProfessorMichaelLevin

Faculty of Medicine, Department of Infectious Disease

Chair in Paediatrics & International Child Health
 
 
 
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Contact

 

+44 (0)20 7594 3760m.levin Website

 
 
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Location

 

233Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Rodgers:2020:10.1016/j.jinf.2020.06.064,
author = {Rodgers, E and Bentley, SD and Borrow, R and Bratcher, HB and Brisse, S and Brueggemann, AB and Caugant, DA and Findlow, J and Fox, L and Glennie, L and Harrison, LH and Harrison, OB and Heyderman, RS and van, Rensburg MJ and Jolley, KA and Kwambana-Adams, B and Ladhani, S and LaForce, M and Levin, M and Lucidarme, J and MacAlasdair, N and Maclennan, J and Maiden, MCJ and Maynard-Smith, L and Muzzi, A and Oster, P and Rodrigues, CMC and Ronveaux, O and Serino, L and Smith, V and van, der Ende A and Vázquez, J and Wang, X and Yezli, S and Stuart, JM},
doi = {10.1016/j.jinf.2020.06.064},
journal = {Journal of Infection},
pages = {510--520},
title = {The global meningitis genome partnership.},
url = {http://dx.doi.org/10.1016/j.jinf.2020.06.064},
volume = {4},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Genomic surveillance of bacterial meningitis pathogens is essential for effective disease control globally, enabling identification of emerging and expanding strains and consequent public health interventions. While there has been a rise in the use of whole genome sequencing, this has been driven predominately by a subset of countries with adequate capacity and resources. Global capacity to participate in surveillance needs to be expanded, particularly in low and middle-income countries with high disease burdens. In light of this, the WHO-led collaboration, Defeating Meningitis by 2030 Global Roadmap, has called for the establishment of a Global Meningitis Genome Partnership that links resources for: N. meningitidis (Nm), S. pneumoniae (Sp), H. influenzae (Hi) and S. agalactiae (Sa) to improve worldwide co-ordination of strain identification and tracking. Existing platforms containing relevant genomes include: PubMLST: Nm (31,622), Sp (15,132), Hi (1935), Sa (9026); The Wellcome Sanger Institute: Nm (13,711), Sp (> 24,000), Sa (6200), Hi (1738); and BMGAP: Nm (8785), Hi (2030). A steering group is being established to coordinate the initiative and encourage high-quality data curation. Next steps include: developing guidelines on open-access sharing of genomic data; defining a core set of metadata; and facilitating development of user-friendly interfaces that represent publicly available data.
AU  - Rodgers,E
AU  - Bentley,SD
AU  - Borrow,R
AU  - Bratcher,HB
AU  - Brisse,S
AU  - Brueggemann,AB
AU  - Caugant,DA
AU  - Findlow,J
AU  - Fox,L
AU  - Glennie,L
AU  - Harrison,LH
AU  - Harrison,OB
AU  - Heyderman,RS
AU  - van,Rensburg MJ
AU  - Jolley,KA
AU  - Kwambana-Adams,B
AU  - Ladhani,S
AU  - LaForce,M
AU  - Levin,M
AU  - Lucidarme,J
AU  - MacAlasdair,N
AU  - Maclennan,J
AU  - Maiden,MCJ
AU  - Maynard-Smith,L
AU  - Muzzi,A
AU  - Oster,P
AU  - Rodrigues,CMC
AU  - Ronveaux,O
AU  - Serino,L
AU  - Smith,V
AU  - van,der Ende A
AU  - Vázquez,J
AU  - Wang,X
AU  - Yezli,S
AU  - Stuart,JM
DO  - 10.1016/j.jinf.2020.06.064
EP  - 520
PY  - 2020///
SN  - 0163-4453
SP  - 510
TI  - The global meningitis genome partnership.
T2  - Journal of Infection
UR  - http://dx.doi.org/10.1016/j.jinf.2020.06.064
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32615197
UR  - https://www.sciencedirect.com/science/article/pii/S0163445320304461?via%3Dihub
UR  - http://hdl.handle.net/10044/1/81174
VL  - 4
ER  -
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