Summary
Michael Loebinger is Professor of Practice (Respiratory Medicine) at the National Heart and Lung Institute and a Consultant Respiratory Physician at the Royal Brompton Hospital.
He undertook his preclinical studies at Cambridge University gaining a First Class Honours in Medical Sciences followed by study at Oxford University for his clinical studies. He was then awarded a Medical Research Council Clinical Research Training Fellowship in 2006 for studies into the use of adult stem cells in lung disease. This resulted in research published in his PhD, which he was awarded by University College London.
His current research aims focus around chronic lung infections, in particular idiopathic bronchiectasis and aspergillus, Pseudomonas and non-tuberculosis mycobacterial infections. He is presently investigating host susceptibility to these infections, in addition to the development of biomarkers to assist in the management of these conditions. He co-chaired the National bronchiectasis guidelines and co-wrote the European bronchiectasis guidelines and National non-tuberculous mycobacteria guidelines. He chaired the British Thoracic Society Specialist Advisory Group for respiratory infections (2013-2016) and is presently secretary of the European Respiratory Society respiratory infection group. He has helped set up national and European research networks, with funding to produce clinical bronchiectasis databases and is the recipient of several prestigious research grants. He also collaborates with Industry and is global, national and site principal investigator of multicentre international clinical trials. He has won young investigator of the year awards from the Royal Society of Medicine, the European Respiratory Society, the British Thoracic Society and the British Association of Lung Research. In addition, he has won prestigious awards from the American Thoracic Society, the Medical Research Society and the British Lung Foundation and was awarded the European Respiratory Society research award for innovation in non-tuberculous Mycobacteria in 2018.
His clinical interests include respiratory infection, particularly host defence abnormalities, bronchiectasis, primary ciliary dyskinesia, primary immunodeficiency, non-tuberculosis mycobacterial infections and cystic fibrosis. He also lead TB at the Royal Brompton and Harefield NHS Foundation Trust, and runs TB clinics at Chelsea and Westminster Hospital. He leads laboratory services at the Royal Brompton and Harefield NHS Foundation Trust as Clinical Director of Laboratory Medicine.
Publications
Journals
Ringshausen FC, Shapiro AJ, Nielsen KG, et al. , 2023, Safety and efficacy of the epithelial sodium channel blocker idrevloride in people with primary ciliary dyskinesia (CLEAN-PCD): a multinational, phase 2, randomised, double-blind, placebo-controlled crossover trial., Lancet Respir Med
Chalmers JD, Polverino E, Crichton ML, et al. , 2023, Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)., Lancet Respir Med, Vol:11, Pages:637-649
Loebinger MR, van der Laan R, Obradovic M, et al. , 2023, Global survey of physician testing practices for nontuberculous mycobacteria., Erj Open Res, Vol:9, ISSN:2312-0541
Dedrick RM, Abad L, Storey N, et al. , 2023, The problem of Mycobacterium abscessus complex: multi-drug resistance, bacteriophage susceptibility and potential healthcare transmission., Clin Microbiol Infect
Loebinger MR, Quint JK, van der Laan R, et al. , 2023, Risk Factors for Nontuberculous Mycobacterial Pulmonary Disease: A Systematic Literature Review and Meta-Analysis., Chest