Imperial College London
Portrait Picture

DrMarcMasen

Faculty of Engineering, Department of Mechanical Engineering

Reader in Tribology and Mechanical Engineering Design
 
 
 
//

Contact

 

+44 (0)20 7594 7066m.masen

 
 
//

Assistant

 

Mrs Chrissy Stevens +44 (0)20 7594 7064

 
//

Location

 

668City and Guilds BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Boyle:2019:10.1126/sciadv.aay0244,
author = {Boyle, C and Plotczyk, M and Fayos, Villalta S and Patel, S and Hettiaratchy, S and Masouros, S and Masen, M and Higgins, C},
doi = {10.1126/sciadv.aay0244},
journal = {Science Advances},
pages = {1--13},
title = {Morphology and composition play distinct and complementary roles in the tolerance of plantar skin to mechanical load},
url = {http://dx.doi.org/10.1126/sciadv.aay0244},
volume = {5},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Plantar skin on the soles of the feet has a distinct morphology and composition that is thought to enhance its tolerance to mechanical loads, although the individual contributions of morphology and composition have never been quantified. Here, we combine multiscale mechanical testing and computational models of load bearing to quantify the mechanical environment of both plantar and nonplantar skin under load. We find that morphology and composition play distinct and complementary roles in plantar skin’s load tolerance. More specifically, the thick stratum corneum provides protection from stress-based injuries such as skin tears and blisters, while epidermal and dermal compositions provide protection from deformation-based injuries such as pressure ulcers. This work provides insights into the roles of skin morphology and composition more generally and will inform the design of engineered skin substitutes as well as the etiology of skin injury.
AU  - Boyle,C
AU  - Plotczyk,M
AU  - Fayos,Villalta S
AU  - Patel,S
AU  - Hettiaratchy,S
AU  - Masouros,S
AU  - Masen,M
AU  - Higgins,C
DO  - 10.1126/sciadv.aay0244
EP  - 13
PY  - 2019///
SN  - 2375-2548
SP  - 1
TI  - Morphology and composition play distinct and complementary roles in the tolerance of plantar skin to mechanical load
T2  - Science Advances
UR  - http://dx.doi.org/10.1126/sciadv.aay0244
UR  - https://advances.sciencemag.org/content/5/10/eaay0244
UR  - http://hdl.handle.net/10044/1/72315
VL  - 5
ER  -
Download