Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Lecturer in Cardiac Molecular Pathology



+44 (0)20 7594 9496m.noseda




OfficeICTEM buildingHammersmith Campus





Michela Noseda is Research Fellow within the Cardiac Myogenesis, Death and Regeneration research group at the National Heart and Lung Institute.

Dr Noseda received her medical training and begun her research training during this period at the Universita Cattolica del Sacro Cuoren in Rome Italy. She has subsequently trained with Dr Anna Lasorella and Dr Antonio Lavarone at Albert Einstein College of Medicine (NY, USA) and at the University of British Columbia under the supervision of Dr Aly Karsan. In this phase of research she studied paediatric cancer and angiogenesis. During studies on vascular development Dr Noseda discovered an important role for the Notch family of proteins in cardiac development. This critical phase of her training prompted the need to further her experience in cardiac development and cardiac disease in one of the top cardiac science laboratories in the world.

Thus, Dr Noseda  joined Professor Michael Schneider’s group at Baylor College of Medicine (Houston Texas, US) where she initiated her work on adult cardiac progenitors. In 2007, she moved to the UK with Professor Schneider and helped set up the new laboratory at Imperial College London where she is  continuing her work on cardiac regeneration and adult heart derived cardiac progenitors.

Dr Noseda is now the senior researcher of Professor Schneider’s group focusing on the molecular and functional characterization of adult derived cardiac progenitors  which are among the best candidates for future cell therapy.



Fiedler LR, Chapman K, Xie M, et al., 2020, MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo (vol 24, 579.e1,2019), Cell Stem Cell, Vol:26, ISSN:1934-5909, Pages:458-458

Schneider M, Fiedler L, Chapman K, et al., 2019, MAP4K4 inhibition promotes survival of human stem cell derived cardiomyocyte and reduces infarct size in vivo, Cell Stem Cell, Vol:24, ISSN:1875-9777, Pages:579-591.e12

Massaia A, Chaves P, Samari S, et al., 2018, Single cell gene expression to understand the dynamic architecture of the heart, Frontiers in Cardiovascular Medicine, Vol:5, ISSN:2297-055X

Shanmuganathan M, Vughs J, Noseda M, et al., 2018, Exosomes: Basic biology and technological advancements suggesting their potential as ischemic heart disease therapeutics, Frontiers in Physiology, Vol:9, ISSN:1664-042X


Noseda M, Samari S, Chaves P, et al., 2019, Modulation of Macrophage Differentiation and Activation: Paracrine Signals from Cardiac Progenitor Cells, SPRINGER, Pages:262-262, ISSN:0920-3206

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