Imperial College London

DrMasahiroOno

Faculty of Natural SciencesDepartment of Life Sciences

Reader in Immunology
 
 
 
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Contact

 

m.ono

 
 
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Location

 

605Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Dr Masahiro Ono is an immunologist and expert in T-cell regulation. His research focuses on mechanisms of T cell activation and regulation in autoimmunity, infections, and cancer. He is the pioneer of the Timer-of-Cell-Kinetics-and-Activity (Tocky, とき), which analyses temporal changes of T-cell activities in vivo using Fluorescent Timer protein.

Dr Ono did his undergraduate in Faculty of Medicine, Kyoto University (1993-1999, MD) and later was trained in dermatology. He did his PhD in 2002 - 2006 in the study of regulatory T cells (Tregs) and the transcription factors Foxp3 and Runx1, starting his immunology career. In 2009, he obtained a HFSP Fellowship, and joined University College London (UCL), when he extended his research to immunological genomics. In 2012, he was awarded a BBSRC David Phillips Fellowship, and established his lab in UCL. He joined Imperial in 2015 and was appointed as a Senior Lecturer in 2018. He was promoted to a Reader in Immunology in 2020.

The lab website

CRUK Convergence Science Centre

Publications

Journals

Whyte CE, Singh K, Burton OT, et al., 2022, Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits., J Exp Med, Vol:219

Whyte CE, Singh K, Burton OT, et al., 2022, Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits., J Exp Med, Vol:219

Hamilton A, Rizzo R, Brod S, et al., 2022, The immunomodulatory effects of social isolation in mice are linked to temperature control, Brain Behavior and Immunity, Vol:102, ISSN:0889-1591, Pages:179-194

Tan BJY, Sugata K, Reda O, et al., 2021, HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma, Journal of Clinical Investigation, Vol:131, ISSN:0021-9738

Bortoluzzi S, Dashtsoodol N, Engleitner T, et al., 2021, Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling, Immunity, Vol:54, ISSN:1074-7613, Pages:2497-+

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