Imperial College London

ProfessorMaryRyan

Faculty of EngineeringDepartment of Materials

Vice-Dean (Research), Faculty of Engineering
 
 
 
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Contact

 

+44 (0)20 7594 6755m.p.ryan

 
 
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Location

 

B338Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Theodorou:2015:10.1039/C5EN00051C,
author = {Theodorou, I and Porter, AE and Ryan, M and leo, BF and López-Heras, M},
doi = {10.1039/C5EN00051C},
journal = {Environmental Science: Nano},
pages = {312--326},
title = {Towards understanding the antibacterial activity of Ag nanoparticles: electron microscopy in the analysis of the materials-biology interface in the lung},
url = {http://dx.doi.org/10.1039/C5EN00051C},
volume = {2},
year = {2015}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Bacterial infections of the pulmonary system are increasing. With almost half of today's infections beingcaused by strains of bacteria that are resistant to existing conventional antibiotics, there is an urgent needfor the development of novel therapeutic platforms. Silver nanoparticles (AgNPs) have been receivingincreasing attention due to their unique antibacterial properties, and whilst the biological efficacy of silveris well known, the mechanisms by which AgNPs degrade within cells and how these processes correlate totheir bioreactivity are poorly understood. This review summarises the current knowledge on thebactericidal pathways of AgNPs and discusses the challenges to be faced before we are able to developefficient and safe antibacterial agents for the treatment of bacterial infections in the lung.
AU - Theodorou,I
AU - Porter,AE
AU - Ryan,M
AU - leo,BF
AU - López-Heras,M
DO - 10.1039/C5EN00051C
EP - 326
PY - 2015///
SN - 2051-8161
SP - 312
TI - Towards understanding the antibacterial activity of Ag nanoparticles: electron microscopy in the analysis of the materials-biology interface in the lung
T2 - Environmental Science: Nano
UR - http://dx.doi.org/10.1039/C5EN00051C
UR - http://hdl.handle.net/10044/1/25009
VL - 2
ER -