Imperial College London

ProfessorMaryRyan

Faculty of EngineeringDepartment of Materials

Vice-Dean (Research), Faculty of Engineering
 
 
 
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Contact

 

+44 (0)20 7594 6755m.p.ryan

 
 
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Location

 

B338Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Othman:2016:10.1002/adhm.201670053,
author = {Othman, BA and Greenwood, C and Abuelela, AF and Bharath, AA and Chen, S and Theodorou, I and Douglas, T and Uchida, M and Ryan, M and Merzaban, JS and Porter, AE},
doi = {10.1002/adhm.201670053},
journal = {Advanced Healthcare Materials},
pages = {1248--1248},
title = {Targeted Cancer Therapy: Correlative Light-Electron Microscopy Shows RGD-Targeted ZnO Nanoparticles Dissolve in the Intracellular Environment of Triple Negative Breast Cancer Cells and Cause Apoptosis with Intratumor Heterogeneity (Adv. Healthcare Mater. 11/2016).},
url = {http://dx.doi.org/10.1002/adhm.201670053},
volume = {5},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - On page 1310 J. S. Merzaban, A. E. Porter, and co-workers present fluorescently labeled RGD-targeted ZnO nanoparticles (NPs; green) for the targeted delivery of cytotoxic ZnO to integrin αvβ3 receptors expressed on triple negative breast cancer cells. Correlative light-electron microscopy shows that NPs dissolve into ionic Zn(2+) (blue) upon uptake and cause apoptosis (red) with intra-tumor heterogeneity, thereby providing a possible strategy for targeted breast cancer therapy. Cover design by Ivan Gromicho.
AU - Othman,BA
AU - Greenwood,C
AU - Abuelela,AF
AU - Bharath,AA
AU - Chen,S
AU - Theodorou,I
AU - Douglas,T
AU - Uchida,M
AU - Ryan,M
AU - Merzaban,JS
AU - Porter,AE
DO - 10.1002/adhm.201670053
EP - 1248
PY - 2016///
SN - 2192-2640
SP - 1248
TI - Targeted Cancer Therapy: Correlative Light-Electron Microscopy Shows RGD-Targeted ZnO Nanoparticles Dissolve in the Intracellular Environment of Triple Negative Breast Cancer Cells and Cause Apoptosis with Intratumor Heterogeneity (Adv. Healthcare Mater. 11/2016).
T2 - Advanced Healthcare Materials
UR - http://dx.doi.org/10.1002/adhm.201670053
VL - 5
ER -