Imperial College London


Faculty of EngineeringDepartment of Materials

Vice-Dean (Research), Faculty of Engineering



+44 (0)20 7594 6755m.p.ryan




B338Royal School of MinesSouth Kensington Campus






BibTex format

author = {Theodorou, I and Jawad, Z and Jiang, Q and Aboagye, E and Porter, A and Ryan, M and Xie, F},
doi = {10.1021/acs.chemmater.7b02313},
journal = {Chemistry of Materials},
pages = {6916--6926},
title = {Gold Nanostar Substrates for Metal Enhanced Fluorescence through the First and Second Near-Infrared Windows},
url = {},
volume = {29},
year = {2017}

RIS format (EndNote, RefMan)

AB - Gold nanostars (AuNSs) are receiving increasing attention for their potential applications in bionanotechnology because of their unique optical properties related to their complex branched morphology. Their sharp features allow strong localized surface plasmon resonances, tunable in the near-infrared (NIR) region, and large enhancements of local electromagnetic fields. Here, the application of AuNSs in metal-enhanced fluorescence (MEF) in the NIR and second NIR (NIR-II) biological windows is explored for the first time. NIR/NIR-II fluorophores are incorporated onto monolayers of AuNSs with tunable plasmonic responses. Over 320-fold fluorescence enhancement is achieved in the NIR, confirming that AuNS substrates are promising NIR-MEF platforms for the development of ultrasensitive biosensing applications. Using fluorescence lifetime measurements to semiquantitatively deconvolute the excitation enhancement from emission enhancement, as well as modeling to simulate the electric field enhancement, we show that a combination of enhanced excitation and an increased radiative decay rate, accompanied by an increase in the quantum yield, contribute to the observed large enhancement. AuNSs with different morphological features exhibit significantly different excitation enhancements, indicating the important role of the particle morphology on the magnitude of electromagnetic field enhancement and the resulting enhancement factor. Importantly, enhancement factors of up to 50-fold are also achieved in the NIR-II region, suggesting that this system holds promise for the future development of bright probes for NIR/NIR-II biosensing and bioimaging.
AU - Theodorou,I
AU - Jawad,Z
AU - Jiang,Q
AU - Aboagye,E
AU - Porter,A
AU - Ryan,M
AU - Xie,F
DO - 10.1021/acs.chemmater.7b02313
EP - 6926
PY - 2017///
SN - 1520-5002
SP - 6916
TI - Gold Nanostar Substrates for Metal Enhanced Fluorescence through the First and Second Near-Infrared Windows
T2 - Chemistry of Materials
UR -
UR -
VL - 29
ER -