Imperial College London

ProfessorMalcolmParker

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Emeritus Professor of Molecular Endocrinology
 
 
 
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Contact

 

+44 (0)20 7594 2177m.parker Website

 
 
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Assistant

 

Miss Kiran Dosanjh +44 (0)20 7594 2176

 
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Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

196 results found

White R, Sjoberg M, Kalkhoven E, Parker MGet al., 1997, Ligand-independent activation of the oestrogen receptor by mutation of a conserved tyrosine, EMBO JOURNAL, Vol: 16, Pages: 1427-1435, ISSN: 0261-4189

Journal article

Collingwood TN, Rajanayagam O, Adams M, Wagner R, Cavailles V, Kalkhoven E, Matthews C, Nystrom E, Stenlof K, Lindstedt G, Tisell L, Fletterick RJ, Parker MG, Chatterjee VKKet al., 1997, A natural transactivation mutation in the thyroid hormone beta receptor: Impaired interaction with putative transcriptional mediators, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 94, Pages: 248-253, ISSN: 0027-8424

Journal article

Parker MG, Kalkhoven E, White R, Henttu P, Sjoberg M, Heery DMet al., 1996, Transcriptional activation by oestrogen receptors., IMMUNOLOGY, Vol: 89, Pages: SP57-SP57, ISSN: 0019-2805

Journal article

LHorset F, Dauvois S, Heery DM, Cavailles V, Parker MGet al., 1996, RIP-140 interacts with multiple nuclear receptors by means of two distinct sites, MOLECULAR AND CELLULAR BIOLOGY, Vol: 16, Pages: 6029-6036, ISSN: 0270-7306

Journal article

Sourdaine P, Mullen P, White R, Telford J, Parker MG, Miller WRet al., 1996, Aromatase activity and CYP19 gene expression in breast cancers, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol: 59, Pages: 191-198, ISSN: 0960-0760

Journal article

Parker MG, 1996, Nuclear receptor superfamily reunion, TRENDS IN GENETICS, Vol: 12, Pages: 277-278, ISSN: 0168-9525

Journal article

Altucci L, Addeo R, Cicatiello L, Dauvois S, Parker MG, Truss M, Beato M, Sica V, Bresciani F, Weisz Aet al., 1996, 17 beta-Estradiol induces cyclin D-1 gene transcription, p36(D1)-p34(cdk4) complex activation and p105(Rb) phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer, ONCOGENE, Vol: 12, Pages: 2315-2324, ISSN: 0950-9232

Journal article

IgnarTrowbridge DM, Pimentel M, Parker MG, McLachlan JA, Korach KSet al., 1996, Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol, ENDOCRINOLOGY, Vol: 137, Pages: 1735-1744, ISSN: 0013-7227

Journal article

Rea D, Parker MG, 1996, Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells, CANCER RESEARCH, Vol: 56, Pages: 1556-1563, ISSN: 0008-5472

Journal article

Parker MG, White R, 1996, Nuclear receptors spring into action, NATURE STRUCTURAL BIOLOGY, Vol: 3, Pages: 113-115, ISSN: 1072-8368

Journal article

Zhang YL, Parker MG, 1996, Studies on the correlation of the TATA-box binding proteins of the rat PSBP C-3 gene with its transcription activities, ACTA BIOCHIMICA ET BIOPHYSICA SINICA, Vol: 28, Pages: 21-28, ISSN: 0582-9879

Journal article

Parker MG, 1996, Antiestrogen-estrogen receptor interactions., Cancer Treat Res, Vol: 83, Pages: 213-224, ISSN: 0927-3042

Journal article

Dauvois S, Parker MG, 1996, Nucleocytoplasmic shuttling of estrogen receptors is blocked by ''pure anti-estrogens'', 2nd International Hormonal Carcinogenesis Symposium, Publisher: SPRINGER-VERLAG, Pages: 79-85

Conference paper

Lahooti H, White R, Hoare SA, Rahman D, Pappin DJC, Parker MGet al., 1995, Identification of phosphorylation sites in the mouse oestrogen receptor, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol: 55, Pages: 305-313, ISSN: 0960-0760

Journal article

BUTLER AJ, PARKER MG, 1995, COUP-TF-II HOMODIMERS ARE FORMED IN PREFERENCE TO HETERODIMERS WITH RXR-ALPHA OR TR-BETA IN INTACT-CELLS, NUCLEIC ACIDS RESEARCH, Vol: 23, Pages: 4143-4150, ISSN: 0305-1048

Journal article

CAVAILLES V, DAUVOIS S, LHORSET F, LOPEZ G, HOARE S, KUSHNER PJ, PARKER MGet al., 1995, NUCLEAR FACTOR RIP140 MODULATES TRANSCRIPTIONAL ACTIVATION BY THE ESTROGEN-RECEPTOR, EMBO JOURNAL, Vol: 14, Pages: 3741-3751, ISSN: 0261-4189

Journal article

PIETRAS RJ, ARBOLEDA J, REESE DM, WONGVIPAT N, PEGRAM MD, RAMOS L, GORMAN CM, PARKER MG, SLIWKOWSKI MX, SLAMON DJet al., 1995, HER-3 TYROSINE KINASE PATHWAY TARGETS ESTROGEN-RECEPTOR AND PROMOTES HORMONE-INDEPENDENT GROWTH IN HUMAN BREAST-CANCER CELLS, ONCOGENE, Vol: 10, Pages: 2435-2446, ISSN: 0950-9232

Journal article

JOBLING S, REYNOLDS T, WHITE R, PARKER MG, SUMPTER JPet al., 1995, A VARIETY OF ENVIRONMENTALLY PERSISTENT CHEMICALS, INCLUDING SOME PHTHALATE PLASTICIZERS, ARE WEAKLY ESTROGENIC, ENVIRONMENTAL HEALTH PERSPECTIVES, Vol: 103, Pages: 582-587, ISSN: 0091-6765

Journal article

LITTLEWOOD TD, HANCOCK DC, DANIELIAN PS, PARKER MG, EVEN GIet al., 1995, A MODIFIED ESTROGEN-RECEPTOR LIGAND-BINDING DOMAIN AS AN IMPROVED SWITCH FOR THE REGULATION OF HETEROLOGOUS PROTEINS, NUCLEIC ACIDS RESEARCH, Vol: 23, Pages: 1686-1690, ISSN: 0305-1048

Journal article

MAHFOUDI A, ROULET E, DAUVOIS S, PARKER MG, WAHLI Wet al., 1995, SPECIFIC MUTATIONS IN THE ESTROGEN-RECEPTOR CHANGE THE PROPERTIES OF ANTIESTROGENS TO FULL AGONISTS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 92, Pages: 4206-4210, ISSN: 0027-8424

Journal article

REA DW, PARKER MG, 1995, STRUCTURE AND FUNCTION OF THE ESTROGEN-RECEPTOR IN RELATION TO ITS ALTERED SENSITIVITY TO ESTRADIOL AND TAMOXIFEN, International Meeting on Current Topics in Breast Cancer Research, Publisher: J ENDOCRINOLOGY LTD, Pages: 13-17, ISSN: 1351-0088

Conference paper

SADOVSKY Y, WEBB P, LOPEZ G, BAXTER JD, FITZPATRICK PM, GIZANGGINSBERG E, CAVAILLES V, PARKER MG, KUSHNER PJet al., 1995, TRANSCRIPTIONAL ACTIVATORS DIFFER IN THEIR RESPONSES TO OVEREXPRESSION OF TATA-BOX-BINDING PROTEIN, MOLECULAR AND CELLULAR BIOLOGY, Vol: 15, Pages: 1554-1563, ISSN: 0270-7306

Journal article

LEWIS DFV, PARKER MG, KING RJB, 1995, MOLECULAR MODELING OF THE HUMAN ESTROGEN-RECEPTOR AND LIGAND INTERACTIONS BASED ON SITE-DIRECTED MUTAGENESIS AND AMINO-ACID-SEQUENCE HOMOLOGY, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol: 52, Pages: 55-65, ISSN: 0960-0760

Journal article

Parker MG, 1995, Structure and function of estrogen receptors, VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 51, Vol: 51, Pages: 267-287, ISSN: 0083-6729

Journal article

SOURDAINE P, PARKER MG, TELFORD J, MILLER WRet al., 1994, ANALYSIS OF THE AROMATASE CYTOCHROME-P450 GENE IN HUMAN BREAST CANCERS, JOURNAL OF MOLECULAR ENDOCRINOLOGY, Vol: 13, Pages: 331-337, ISSN: 0952-5041

Journal article

SAVOURET JF, RAUCH M, REDEUILH G, SAR S, CHAUCHEREAU A, WOODRUFF K, PARKER MG, MILGROM Eet al., 1994, INTERPLAY BETWEEN ESTROGENS, PROGESTINS, RETINOIC ACID AND AP-1 ON A SINGLE REGULATORY SITE IN THE PROGESTERONE-RECEPTOR GENE, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 269, Pages: 28955-28962, ISSN: 0021-9258

Journal article

CAVAILLES V, DAUVOIS S, DANIELIAN PS, PARKER MGet al., 1994, INTERACTION OF PROTEINS WITH TRANSCRIPTIONALLY ACTIVE ESTROGEN-RECEPTORS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 91, Pages: 10009-10013, ISSN: 0027-8424

Journal article

WHITE R, JOBLING S, HOARE SA, SUMPTER JP, PARKER MGet al., 1994, ENVIRONMENTALLY PERSISTENT ALKYLPHENOLIC COMPOUNDS ARE ESTROGENIC, ENDOCRINOLOGY, Vol: 135, Pages: 175-182, ISSN: 0013-7227

Journal article

PUROHIT A, DAUVOIS S, PARKER MG, POTTER BVL, WILLIAMS GJ, REED MJet al., 1994, THE HYDROLYSIS OF ESTRONE SULFATE AND DEHYDROEPIANDROSTERONE-SULFATE BY HUMAN STEROID SULFATASE EXPRESSED IN TRANSFECTED COS-1 CELLS, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol: 50, Pages: 101-104, ISSN: 0960-0760

Journal article

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