Dr Michelle Percharde is an epigenetics and stem cell biologist and head of the Chromatin and Development Group at the MRC LMS.
Her work focuses on understanding the interplay between transposable elements, chromatin regulation and cell fate choices during early development.
She carried out her undergraduate degree in Biochemistry at the University of Cambridge and PhD in reprogramming and nuclear receptors at Imperial College, London. In 2013, she moved to UCSF in San Francisco, USA, and was awarded a CIRM postdoctoral fellowship to carry out her postdoctoral training with Prof. Miguel Ramalho-Santos. She moved to Imperial College as an independent fellow in 2018.
Percharde M, Lin CJ, Ramalho-Santos M, 2021, Depletion of nuclear LINE1 RNA in mouse ESCs and embryos, Star Protocols, Vol:2
et al., 2021, Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome, Cell Research, Vol:31, ISSN:1001-0602, Pages:613-630
et al., 2020, Delineating the early transcriptional specification of the mammalian trachea and esophagus, Elife, Vol:9
et al., 2020, Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation, Cell Reports, Vol:30, ISSN:2211-1247, Pages:3296-+
et al., 2018, A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity, Cell, Vol:174, ISSN:0092-8674, Pages:391-+