Publications
655 results found
Jones S, Kon S, Canavan J, et al., 2014, Phase angle versus conventional bioelectric impedance analysis in patients hospitalised with an acute exacerbation of COPD, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Kon S, Jones S, Miller B, et al., 2014, Serum adiponectin in hospitalised patients with CORD: Relationship with peripheral muscle function, physical performance and readmissions, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Xiao S, Wu Y, He B, et al., 2014, Neural respiratory drive and arousal in patien s obstructive sleep apnea hypopnea, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Nolan CM, Canavan JL, Kon SSC, et al., 2014, The minimum important difference (MID) of the incremental shuttle walk (ISW) in COPD: Does baseline ISW influence estimates?, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Kon S, Jones S, Schofield S, et al., 2014, Gait speed is a predictor of readmission following hospitalisation for acute exacerbations of COPD, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Maddocks M, Kon S, Jones S, et al., 2014, Validity of phase angle as a health indicator in stable COPD, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Duenas-Espin I, Demeyer H, Gimeno-Santos E, et al., 2014, Longitudinal effects of a iety and depression on physical activity in COPD patients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Duenas-Espin I, Demeyer H, Gimeno-Santos E, et al., 2014, Longitudinal effects of anxiety and depression on physical activity in COPD patients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Pagliaroli E, Mohan D, Padmanaban V, et al., 2014, Elevated cardiovascular risk as measured by QRISK2 score in patients hospitalized for acute COPD exacerbation <i>versus</i> stable COPD outpatients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Boutou A, Zoumot Z, Davey C, et al., 2014, Association between dynamic hyperinflation and emphysema distribution in COPD patients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Franks R, Boutou A, Mohan D, et al., 2014, Dynamics of QT interval from rest to peak exercise among COPD patients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Zoumot Z, Lo Maoro A, Aliverti A, et al., 2014, Successful lung volume reduction improves inspiratory paradoxical movement of the lower rib cage at rest as measured by optoelectronic plethysmography, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Mesquite R, Spina G, Pitta F, et al., 2014, Cluster analysis of objectively measured physical activity in 1001 COPD patients, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Davey C, Zoumot Z, McNulty W, et al., 2014, Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (BeLieVeR-HIFi), 22nd Annual Congress of the European-Respiratory-Society, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Patel MS, Natanek SA, Stratakos G, et al., 2014, Vastus lateralis fiber shift is an independent predictor of mortality in chronic obstructive pulmonary disease, American Journal of Respiratory and Critical Care Medicine, Vol: 190, Pages: 350-352, ISSN: 1073-449X
Ming DKY, Patel MS, Hopkinson NS, et al., 2014, The 'anatomic shunt test' in clinical practice; contemporary description of test and in-service evaluation, THORAX, Vol: 69, Pages: 773-775, ISSN: 0040-6376
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- Citations: 4
Steier J, Lunt A, Hart N, et al., 2014, Observational study of the effect of obesity on lung volumes, THORAX, Vol: 69, Pages: 752-759, ISSN: 0040-6376
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- Citations: 117
Luo Y-M, He B-T, Wu Y-X, et al., 2014, Neural Respiratory Drive and Ventilation in Patients with Chronic Obstructive Pulmonary Disease during Sleep, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 190, Pages: 227-229, ISSN: 1073-449X
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- Citations: 18
Kon SSC, Canavan JL, Nolan CM, et al., 2014, What the 4-metre gait speed measures and why it cannot replace functional capacity tests, EUROPEAN RESPIRATORY JOURNAL, Vol: 43, Pages: 1820-1822, ISSN: 0903-1936
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- Citations: 6
Maltais F, Decramer M, Casaburi R, et al., 2014, An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease., Am J Respir Crit Care Med, Vol: 189, Pages: e15-e62
BACKGROUND: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease (COPD) and it has important clinical implications, such as reduced exercise tolerance, quality of life, and even survival. Since the previous American Thoracic Society/European Respiratory Society (ATS/ERS) statement on limb muscle dysfunction, important progress has been made on the characterization of this problem and on our understanding of its pathophysiology and clinical implications. PURPOSE: The purpose of this document is to update the 1999 ATS/ERS statement on limb muscle dysfunction in COPD. METHODS: An interdisciplinary committee of experts from the ATS and ERS Pulmonary Rehabilitation and Clinical Problems assemblies determined that the scope of this document should be limited to limb muscles. Committee members conducted focused reviews of the literature on several topics. A librarian also performed a literature search. An ATS methodologist provided advice to the committee, ensuring that the methodological approach was consistent with ATS standards. RESULTS: We identified important advances in our understanding of the extent and nature of the structural alterations in limb muscles in patients with COPD. Since the last update, landmark studies were published on the mechanisms of development of limb muscle dysfunction in COPD and on the treatment of this condition. We now have a better understanding of the clinical implications of limb muscle dysfunction. Although exercise training is the most potent intervention to address this condition, other therapies, such as neuromuscular electrical stimulation, are emerging. Assessment of limb muscle function can identify patients who are at increased risk of poor clinical outcomes, such as exercise intolerance and premature mortality. CONCLUSIONS: Limb muscle dysfunction is a key systemic consequence of COPD. However, there are still important gaps in our knowledge about the mechanisms of development of this problem. Strategie
Patel MS, Mohan D, Andersson YM, et al., 2014, Phenotypic Characteristics Associated With Reduced Short Physical Performance Battery Score in COPD, CHEST, Vol: 145, Pages: 1016-1024, ISSN: 0012-3692
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- Citations: 48
Kon SSC, Canavan JL, Nolan CM, et al., 2014, The 4-metre gait speed in COPD: responsiveness and minimal clinically important difference, EUROPEAN RESPIRATORY JOURNAL, Vol: 43, Pages: 1298-1305, ISSN: 0903-1936
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- Citations: 70
Clark SJ, Zoumot Z, Bamsey O, et al., 2014, Surgical approaches for lung volume reduction in emphysema, CLINICAL MEDICINE, Vol: 14, Pages: 122-127, ISSN: 1470-2118
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- Citations: 42
Shaikh ZF, Kelly JL, Shrikrishna D, et al., 2014, Patent Foramen Ovale Is Not Associated with Hypoxemia in Severe Chronic Obstructive Pulmonary Disease and Does Not Impair Exercise Performance, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, Pages: 540-547, ISSN: 1073-449X
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- Citations: 14
Kon SSC, Canavan JL, Jones SE, et al., 2014, Minimum clinically important difference for the COPD Assessment Test: a prospective analysis, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 195-203, ISSN: 2213-2600
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- Citations: 402
Murphy PB, Zoumot Z, Polkey MI, 2014, Noninvasive ventilation and lung volume reduction., Clin Chest Med, Vol: 35, Pages: 251-269
As parenchymal lung disease in chronic obstructive pulmonary disease becomes increasingly severe there is a diminishing prospect of drug therapies conferring clinically useful benefit. Lung volume reduction surgery is effective in patients with heterogenous upper zone emphysema and reduced exercise tolerance, and is probably underused. Rapid progress is being made in nonsurgical approaches to lung volume reduction, but use outside specialized centers cannot be recommended presently. Noninvasive ventilation given to patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease reduces mortality and morbidity, but the place of chronic non-invasive ventilatory support remains more controversial.
Guleria R, Lyall R, Hart N, et al., 2014, Central fatigue of the diaphragm and quadriceps during incremental loading, LUNG, Vol: 180, Pages: 1-13, ISSN: 0341-2040
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- Citations: 13
Jolley C, Luo Y-M, Steier J, et al., 2014, Neural respiratory drive and breathlessness during incremental cycle and treadmill exercise in chronic obstructive pulmonary disease, LANCET, Vol: 383, Pages: 63-63, ISSN: 0140-6736
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- Citations: 1
Shrikrishna D, Tanner RJ, Lee JY, et al., 2014, A Randomized Controlled Trial of Angiotensin-Converting Enzyme Inhibition for Skeletal Muscle Dysfunction in COPD, Chest, Vol: 146, Pages: 932-940, ISSN: 1931-3543
Gimeno-Santos E, Frei A, Steurer-Stey C, et al., 2014, Determinants and outcomes of physical activity in patients with COPD: a systematic review, Thorax, Vol: 69, Pages: 731-739, ISSN: 1468-3296
Background The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise studies assessing associations between physical activity and its determinants and/or outcomes in patients with COPD and to develop a conceptual model for physical activity in COPD.Methods We conducted a systematic search of four databases (Medline, Embase, CINAHL and Psychinfo) prior to November 2012. Teams of two reviewers independently selected articles, extracted data and used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to assess quality of evidence.Results 86 studies were included: 59 were focused on determinants, 23 on outcomes and 4 on both. Hyperinflation, exercise capacity, dyspnoea, previous exacerbations, gas exchange, systemic inflammation, quality of life and self-efficacy were consistently related to physical activity, but often based on cross-sectional studies and low-quality evidence. Results from studies of pharmacological and non-pharmacological treatments were inconsistent and the quality of evidence was low to very low. As outcomes, COPD exacerbations and mortality were consistently associated with low levels of physical activity based on moderate quality evidence. Physical activity was associated with other outcomes such as dyspnoea, health-related quality of life, exercise capacity and FEV1 but based on cross-sectional studies and low to very low quality evidence.Conclusions Physical activity level in COPD is consistently associated with mortality and exacerbations, but there is poor evidence about determinants of physical activity, including the impact of treatment.
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