Imperial College London
Dr Marie-Christine Ramel

DrMarie-ChristineRamel

Faculty of Natural Sciences, Department of Life Sciences

Visiting Researcher
 
 
 
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Contact

 

+44 (0)20 7594 5405m.ramel

 
 
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Location

 

6150Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ramel:2012:10.1016/j.febslet.2012.02.035,
author = {Ramel, M-C and Hill, CS},
doi = {10.1016/j.febslet.2012.02.035},
journal = {FEBS Lett},
pages = {1929--1941},
title = {Spatial regulation of BMP activity.},
url = {http://dx.doi.org/10.1016/j.febslet.2012.02.035},
volume = {586},
year = {2012}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The bone morphogenetic protein (BMP) signalling pathway is critical for embryonic development and tissue homeostasis, and impaired BMP signalling has been implicated in multiple diseases. Molecular tools have been developed to visualise BMP activity in vivo and these have allowed a better understanding of the intricate ways in which BMP activity is regulated spatially. In particular, generation and interpretation of BMP activity gradients during development result from the complex interplay between core BMP signalling components and specific regulators. In this essay we discuss the mechanisms by which spatial regulation of BMP activity is achieved and its functional consequences.
AU  - Ramel,M-C
AU  - Hill,CS
DO  - 10.1016/j.febslet.2012.02.035
EP  - 1941
PY  - 2012///
SP  - 1929
TI  - Spatial regulation of BMP activity.
T2  - FEBS Lett
UR  - http://dx.doi.org/10.1016/j.febslet.2012.02.035
UR  - https://www.ncbi.nlm.nih.gov/pubmed/22710177
VL  - 586
ER  -
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