Imperial College London

DrMaxieRoessler

Faculty of Natural SciencesDepartment of Chemistry

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 9861m.roessler Website

 
 
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Location

 

301AMolecular Sciences Research HubWhite City Campus

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Summary

 

Summary

Redox reactions underpin innumerable chemical reactions - and much of the chemistry of life! I am fascinated by how oxidation-state changes govern respiration and photosynthesis and how nature has fine-tuned the redox properties of its many intricate molecular machines. Redox reactions often involve transition metal ions and in the group we are investigating the properties, structure and bonding of transition-metal centres in both biological and synthetic molecular machines. 

Many redox reactions proceed via radical intermediates and these are, perhaps luckily, often located in mechanistically key locations. In the lab, we use electron paramagnetic resonance (EPR) spectroscopy as a powerful method for obtaining detailed information on the structure and bonding these ubiquitous spin centres. Electrochemistry on the other hand, in particular film electrochemistry, provides insight into the reactions carried out by molecular machines. These (bio)physical methods are supplemented by biochemical and synthetic methods. 

Biography


I completed my DPhil at the University of Oxford in 2012 under the supervision of Prof. Fraser Armstrong FRS, working primarily on hydrogenases and on understanding how these enzymes are such exceptionally good H2 producers/oxidisers, even in the presence of oxygen. After a one-year PostDoc in the same group, followed by maternity leave, I started my independent career at the School of Biological and Chemical Sciences at Queen Mary University of London in 2013 and was promoted to senior lecturer in 2018. Following another maternity (shared parental) leave, I moved to Imperial College in April 2019. 

Publications

Journals

Luo H, Papaioannou N, Salvadori E, et al., 2019, Manipulating the Optical Properties of Carbon Dots by Fine-Tuning their Structural Features, Chemsuschem, Vol:12, ISSN:1864-5631, Pages:4480-4486

Mellor SB, Vinde MH, Nielsen AZ, et al., 2019, Defining optimal electron transfer partners for light-driven cytochrome P450 reactions, Metabolic Engineering, Vol:55, ISSN:1096-7176, Pages:33-43

Cirulli M, Kaur A, Lewis JEM, et al., 2019, Rotaxane-based transition metal complexes: Effect of the mechanical bond on structure and electronic properties, Journal of the American Chemical Society, Vol:141, ISSN:0002-7863, Pages:879-889

Abdiaziz K, Salvadori E, Sokol K, et al., Protein film electrochemical EPR spectroscopy as a technique to investigate redox reactions in biomolecules, Chemical Communications, ISSN:1359-7345

Martinez-Lumbreras S, Krysztofinska EM, Thapaliya A, et al., 2018, Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control, Bmc Biology, Vol:16, ISSN:1741-7007

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