Summary
Michelle Wortley is a postdoctoral research associate within the department of Bioengineering delivering technology innovation for multiple clinical applications. Projects include monitoring brain tissue health in traumatic brain injury patients, assessing kidney viability prior to transplantation, monitoring compartment syndrome onset, development of in vivo antibiotic sensors, and monitoring tissue perfusion during free-flap reconstruction surgery. The technology uses electrochemical biosensors are fabricated within a 3D printed microfluidic manifold that is housed in a wireless device suitable for continuous bed-side monitoring in hospitals.
In December 2011, Michelle was awarded her PhD in Bioengineering at Imperial College. Prior to post-graduate studies Michelle was awarded a BSc in Human Genetics from University College London.
Publications
Journals
Gowers S, Samper I, Murray D-S, et al., 2020, Real-time neurochemical measurement of dynamic metabolic events during cardiac arrest and resuscitation in a porcine model, The Analyst, Vol:145, ISSN:0003-2654, Pages:1894-1902
Gowers S, Rogers M, Booth M, et al., 2019, Clinical translation of microfluidic sensor devices: Focus on calibration and analytical robustness, Lab on a Chip, Vol:19, ISSN:1473-0189, Pages:2537-2548
Samper I, Gowers S, Rogers M, et al., 2019, 3D printed microfluidic device for online detection of dynamic metabolite concentration changes with high temporal resolution in human brain microdialysate, Lab on a Chip, Vol:19, ISSN:1473-0189, Pages:2038-2048
Gowers SAN, Freeman DME, Rawson TM, et al., 2019, Development of a minimally invasive microneedle-based sensor for continuous monitoring of β-lactam antibiotic concentrations in vivo, Acs Sensors, Vol:4, ISSN:2379-3694, Pages:1072-1080
Conference
Charalampidis S, Gowers S, Rogers M, et al., 2019, CONTINUOUS ONLINE MICRODIALYSIS AS A NOVEL TOOL FOR CONTINUOUS CREATININE MEASUREMENT AND PARENCHYMA ASSESSMENT DURING NORMOTHERMIC MACHINE PERFUSION IN A TRANSLATIONAL EX VIVO PORCINE KIDNEY MODEL, WILEY, Pages:425-425, ISSN:0934-0874