Murray Selkirk earned his PhD at the National Institute for Medical Research, Mill Hill, where he studied immunosuppression in murine trypanosomiasis with Bridget Ogilvie. He then joined the University of Washington, Seattle, working with Nina Agabian on antigenic variation in trypanosomes, and after a brief spell at the Naval Biosciences Laboratory in Oakland, joined Rick Maizels at Imperial College, switching his attention to nematode parasites, in particular those responsible for lymphatic filariasis. He was appointed to a Lectureship in the Department of Biochemistry in 1986, and is currently Professor of Biochemical Parasitology. His research group works on nematode parasites, aiming primarily to understand how these pathogens effect long-term survival in mammalian hosts, with a particular focus on molecular mechanisms underlying regulation of the host immune system and resistance to immunity.
et al., 2022, Differential regulation of allergic airway inflammation by acetylcholine, Frontiers in Immunology, Vol:13, ISSN:1664-3224
et al., 2021, MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function, Journal of Immunology, Vol:206, ISSN:0022-1767, Pages:2725-2739
et al., 2021, ILC3-derived acetylcholine promotes protease-driven allergic lung pathology, Journal of Allergy and Clinical Immunology, Vol:147, ISSN:0091-6749, Pages:1513-1516.E4
et al., 2021, Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths, Science Immunology, Vol:6, ISSN:2470-9468
Hagen J, Sarkies P, Selkirk ME, 2021, Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis, Plos Pathogens, Vol:17, ISSN:1553-7366