Summary
Murray Selkirk earned his PhD at the National Institute for Medical Research, Mill Hill, where he studied immunosuppression in murine trypanosomiasis with Bridget Ogilvie. He then joined the University of Washington, Seattle, working with Nina Agabian on antigenic variation in trypanosomes, and after a brief spell at the Naval Biosciences Laboratory in Oakland, joined Rick Maizels at Imperial College, switching his attention to nematode parasites, in particular those responsible for lymphatic filariasis. He was appointed to a Lectureship in the Department of Biochemistry in 1986, and is currently Professor of Biochemical Parasitology. His research group works on nematode parasites, aiming primarily to understand how these pathogens effect long-term survival in mammalian hosts, with a particular focus on molecular mechanisms underlying regulation of the host immune system and resistance to immunity.
Publications
Journals
Hagen J, Ghosh S, Sarkies P, et al., 2023, Gene editing in the nematode parasite Nippostrongylus brasiliensis using extracellular vesicles to deliver active Cas9/guide RNA complexes, Frontiers in Parasitology, Vol:2, ISSN:2813-2424, Pages:1-14
Almeida-Santos J, Berkachy R, Tye CA, et al., 2022, Temporal profiling of CD4 T-cell activation and differentiation upon SARS-CoV-2 spike protein immunisation
Roberts L, Berkachy R, Wane M, et al., 2022, Differential regulation of allergic airway inflammation by acetylcholine, Frontiers in Immunology, Vol:13, ISSN:1664-3224
Culerier E, Togbe D, Maillet I, et al., 2022, Respiratory research days (J2R) (vol 39, pg 108-131, 2022), Revue Des Maladies Respiratoires, Vol:39, ISSN:0761-8425
Roberts LB, Jowett GM, Read E, et al., 2021, MicroRNA-142 critically regulates group 2 innate lymphoid cell homeostasis and function, Journal of Immunology, Vol:206, ISSN:0022-1767, Pages:2725-2739