Publications
155 results found
Maizels RM, Blaxter ML, Robertson BD, et al., 1991, Parasite Antigens, Parasite Genes: A laboratory manual for molecular parasitology., Cambridge, Publisher: Cambridge University Press, ISBN: 9780521419277
OGILVIE BM, SELKIRK ME, MAIZELS RM, 1990, THE MOLECULAR REVOLUTION AND NEMATODE PARASITOLOGY - YESTERDAY, TODAY, AND TOMORROW, JOURNAL OF PARASITOLOGY, Vol: 76, Pages: 607-618, ISSN: 0022-3395
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- Citations: 4
SELKIRK ME, GREGORY WF, YAZDANBAKHSH M, et al., 1990, CUTICULAR LOCALIZATION AND TURNOVER OF THE MAJOR SURFACE GLYCOPROTEIN (GP29) OF ADULT BRUGIA-MALAYI, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 42, Pages: 31-43, ISSN: 0166-6851
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- Citations: 44
SELKIRK ME, BLAXTER ML, 1990, CUTICULAR PROTEINS OF BRUGIA FILARIAL PARASITES, ACTA TROPICA, Vol: 47, Pages: 373-380, ISSN: 0001-706X
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- Citations: 19
MAIZELS RM, SELKIRK ME, AGNEW A, 1989, PROSPECTS FOR NEW VACCINES AGAINST HELMINTH-PARASITES, TRENDS IN BIOTECHNOLOGY, Vol: 7, Pages: 316-321, ISSN: 0167-7799
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- Citations: 3
KWANLIM GE, GREGORY WF, SELKIRK ME, et al., 1989, SECRETED ANTIGENS OF FILARIAL NEMATODES - A SURVEY AND CHARACTERIZATION OF INVITRO EXCRETED SECRETED PRODUCTS OF ADULT BRUGIA-MALAYI, PARASITE IMMUNOLOGY, Vol: 11, Pages: 629-654, ISSN: 0141-9838
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- Citations: 30
SELKIRK ME, DENHAM DA, PARTONO F, et al., 1989, HEAT-SHOCK COGNATE-70 IS A PROMINENT IMMUNOGEN IN BRUGIAN FILARIASIS, JOURNAL OF IMMUNOLOGY, Vol: 143, Pages: 299-308, ISSN: 0022-1767
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- Citations: 79
BARNES DA, MOTTRAM J, SELKIRK M, et al., 1989, 2 VARIANT SURFACE GLYCOPROTEIN GENES DISTINGUISH BETWEEN DIFFERENT SUBSTRAINS OF TRYPANOSOMA-BRUCEI-GAMBIENSE, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 34, Pages: 135-146, ISSN: 0166-6851
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- Citations: 12
MAIZELS RM, GREGORY WF, KWANLIM GE, et al., 1989, FILARIAL SURFACE-ANTIGENS - THE MAJOR 29 KILODALTON GLYCOPROTEIN AND A NOVEL 17-200 KILODALTON COMPLEX FROM ADULT BRUGIA-MALAYI PARASITES, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 32, Pages: 213-227, ISSN: 0166-6851
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- Citations: 80
SELKIRK ME, NIELSEN L, KELLY C, et al., 1989, IDENTIFICATION, SYNTHESIS AND IMMUNOGENICITY OF CUTICULAR COLLAGENS FROM THE FILARIAL NEMATODES BRUGIA-MALAYI AND BRUGIA-PAHANGI, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 32, Pages: 229-246, ISSN: 0166-6851
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- Citations: 70
Helm R, Selkirk ME, Bradley JE, et al., 1989, Localization and immunogenicity of tubulin in the filarial nematodes Brugei malayi and B. pahangi, Parasitology Immunology, Vol: 11, Pages: 479-502
MAIZELS RM, MORGAN TM, GREGORY WF, et al., 1988, CIRCULATING ANTIBODIES AND ANTIGENS IN PRESBYTIS MONKEYS INFECTED WITH THE FILARIAL PARASITE WUCHERERIA-BANCROFTI, TROPICAL MEDICINE AND PARASITOLOGY, Vol: 39, Pages: 214-220, ISSN: 0177-2392
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- Citations: 7
MAIZELS RM, SELKIRK ME, 1988, ANTIGENS OF FILARIAL PARASITES, ISI ATLAS OF SCIENCE-IMMUNOLOGY, Vol: 1, Pages: 143-148, ISSN: 0894-3745
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- Citations: 9
Maizels RM, Selkirk ME, 1988, Immunobiology of Nematode Antigens, Biology of Parasitism, Editors: Englund, Sher, New Yorl, Publisher: A. R. Liss, Pages: 285-308
RATHAUR S, ROBERTSON BD, SELKIRK ME, et al., 1987, SECRETORY ACETYLCHOLINESTERASES FROM BRUGIA-MALAYI ADULT AND MICROFILARIAL PARASITES, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 26, Pages: 257-265, ISSN: 0166-6851
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- Citations: 54
SELKIRK M, RUTHERFORD P, PARTONO F, et al., 1987, ANTIGEN EXPRESSION IN BRUGIA LYMPHATIC FILARIAE, JOURNAL OF CELLULAR BIOCHEMISTRY, Pages: 145-145, ISSN: 0730-2312
Maizels RM, Selkirk ME, Sutanto I, et al., 1987, Antibody responses to human lymphatic filarial parasites, Filariasis: Ciba Foundation Symposium 127, Pages: 189-202
SELKIRK ME, RUTHERFORD PJ, DENHAM DA, et al., 1987, CLONED ANTIGEN GENES OF BRUGIA FILARIAL PARASITES, BIOCHEMICAL SOCIETY SYMPOSIA, Pages: 91-102, ISSN: 0067-8694
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- Citations: 31
MAIZELS RM, SELKIRK ME, SUTANTO I, et al., 1987, ANTIBODY-RESPONSES TO HUMAN LYMPHATIC FILARIAL PARASITES, CIBA FOUNDATION SYMPOSIA, Vol: 127, Pages: 189-202, ISSN: 0300-5208
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- Citations: 25
Maizels RM, Bianco AE, Flint JE, et al., 1987, Glycoconjugate antigens from parasitic nematodes., Pages: 267-279
Selkirk ME, Rutherford PJ, Bianco AE, et al., 1987, Characterisation and cloning of lymphatic filarial antigens, Pages: 169-181
Selkirk ME, Rutherford PJ, Denham DA, et al., 1987, Cloned antigen genes of Brugia filarial parasites., Biochem Soc Symp, Vol: 53, Pages: 91-102, ISSN: 0067-8694
Human lymphatic filariasis is a chronic, potentially debilitating disease caused by Brugia and Wuchereria species of parasitic nematodes. The spectrum of clinical manifestations appears to be related to the immune response of individuals to invasive larvae, adult worms and circulating first-stage larvae (microfilariae). Potential immunopathological outcomes place constraints on vaccine development, emphasizing the need to understand the basis of immunity and pathology. Clones coding for a number of distinct antigenic proteins of Brugia pahangi and Brugia malayi have been isolated via immunological screening of a cDNA expression library. A small number of these expressed peptides show exclusive reactivity with antibody from amicrofilaraemic, potentially immune individuals. Surprisingly, a dominant immunogen isolated with human antibody is the filarial parasite homologue of heat shock protein (hsp) 70. This protein is constitutively expressed in both insect- and mammalian-dwelling parasitic stages, but does not appear to presented to the host immune system in intact worms.
Selkirk ME, Denham DA, Partono F, et al., 1986, Molecular characterization of antigens of lymphatic filarial parasites., Parasitology, Vol: 92 Suppl, Pages: S15-S38, ISSN: 0031-1820
SELKIRK ME, DENHAM DA, PARTONO F, et al., 1986, MOLECULAR CHARACTERIZATION OF ANTIGENS OF LYMPHATIC FILARIAL PARASITES, PARASITOLOGY, Vol: 92, Pages: S15-S38, ISSN: 0031-1820
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- Citations: 24
Agabian N, Nelson RG, Parson M, et al., 1985, Antigenic Variation and the role of the spliced leader sequence in trypanosomatid gene expression, Pages: 153-172
NELSON RG, PARSONS M, SELKIRK M, et al., 1984, SEQUENCES HOMOLOGOUS TO VARIANT ANTIGEN MESSENGER-RNA SPLICED LEADER IN TRYPANOSOMATIDAE WHICH DO NOT UNDERGO ANTIGENIC VARIATION, NATURE, Vol: 308, Pages: 665-667, ISSN: 0028-0836
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- Citations: 68
Selkirk ME, Newport GR, Milhausen M, et al., 1984, Cloning of predominant variant surface antigen genes of T. b. gambiense, Pages: 219-224
NELSON RG, PARSONS M, BARR PJ, et al., 1983, SEQUENCES HOMOLOGOUS TO THE VARIANT ANTIGEN MESSENGER-RNA SPLICED LEADER ARE LOCATED IN TANDEM REPEATS AND VARIABLE ORPHONS IN TRYPANOSOMA-BRUCEI, CELL, Vol: 34, Pages: 901-909, ISSN: 0092-8674
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- Citations: 123
SELKIRK ME, WILKINS SR, OGILVIE BM, et al., 1983, INVITRO INDUCTION OF HUMAN HELPER T-CELL ACTIVITY BY TRYPANOSOMA-BRUCEI, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 52, Pages: 512-518, ISSN: 0009-9104
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- Citations: 7
SELKIRK ME, OGILVIE BM, PLATTSMILLS TAE, 1981, ACTIVATION OF HUMAN PERIPHERAL-BLOOD LYMPHOCYTES BY A TRYPANOSOME-DERIVED MITOGEN, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 45, Pages: 615-620, ISSN: 0009-9104
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- Citations: 19
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