Publications

BibTex format

@article{Alvaro-Lozano:2020:10.1111/pai.13189,
author = {Alvaro-Lozano, M and Akdis, CA and Akdis, M and Alviani, C and Angier, E and Arasi, S and Arzt-Gradwohl, L and Barber, D and Bazire, R and Cavkaytar, O and Comberiati, P and Dramburg, S and Durham, SR and Eifan, AO and Forchert, L and Halken, S and Kirtland, M and Kucuksezer, UC and Layhadi, JA and Matricardi, PM and Muraro, A and Ozdemir, C and Pajno, GB and Pfaar, O and Potapova, E and Riggioni, C and Roberts, G and Rodriguez, del Rio P and Shamji, MH and Sturm, GJ and Vazquez-Ortiz, M},
doi = {10.1111/pai.13189},
journal = {Pediatric Allergy and Immunology},
pages = {1--101},
title = {Allergen Immunotherapy in Children User’s Guide},
url = {http://dx.doi.org/10.1111/pai.13189},
volume = {31},
year = {2020}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical efficiency relies on a well-defined immunologic mechanism promoting regulatory T cells and downplaying the immune response induced by allergens. Clinical indications have been well documented for respiratory allergy in the presence of rhinitis and/or allergic asthma, to pollens and dust mites. Patients who have had an anaphylactic reaction to hymenoptera venom are also good candidates for allergen immunotherapy. Administration of allergen is currently mostly either by subcutaneous injections or by sublingual administration. Both methods have been extensively studied and have pros and cons. Specifically in children, the choice of the method of administration according to the patient's profile is important. Although allergen immunotherapy is widely used, there is a need for improvement. More particularly, biomarkers for prediction of the success of the treatments are needed. The strength and efficiency of the immune response may also be boosted by the use of better adjuvants. Finally, novel formulations might be more efficient and might improve the patient's adherence to the treatment. This user's guide reviews current knowledge and aims to provide clinical guidance to healthcare professionals taking care of children undergoing allergen immunotherapy.
AU  - Alvaro-Lozano,M
AU  - Akdis,CA
AU  - Akdis,M
AU  - Alviani,C
AU  - Angier,E
AU  - Arasi,S
AU  - Arzt-Gradwohl,L
AU  - Barber,D
AU  - Bazire,R
AU  - Cavkaytar,O
AU  - Comberiati,P
AU  - Dramburg,S
AU  - Durham,SR
AU  - Eifan,AO
AU  - Forchert,L
AU  - Halken,S
AU  - Kirtland,M
AU  - Kucuksezer,UC
AU  - Layhadi,JA
AU  - Matricardi,PM
AU  - Muraro,A
AU  - Ozdemir,C
AU  - Pajno,GB
AU  - Pfaar,O
AU  - Potapova,E
AU  - Riggioni,C
AU  - Roberts,G
AU  - Rodriguez,del Rio P
AU  - Shamji,MH
AU  - Sturm,GJ
AU  - Vazquez-Ortiz,M
DO  - 10.1111/pai.13189
EP  - 101
PY  - 2020///
SN  - 0905-6157
SP  - 1
TI  - Allergen Immunotherapy in Children User’s Guide
T2  - Pediatric Allergy and Immunology
UR  - http://dx.doi.org/10.1111/pai.13189
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000535219600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/82230
VL  - 31
ER  -

Download

ProfessorMohamedShamji

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)