Imperial College London

Professor Molly Stevens

Faculty of EngineeringDepartment of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
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Contact

 

+44 (0)20 7594 6804m.stevens

 
 
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Location

 

208Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Khodabukus:2022:10.1126/scitranslmed.abn9074,
author = {Khodabukus, A and Guyer, T and Moore, AC and Stevens, MM and Guldberg, RE and Bursac, N},
doi = {10.1126/scitranslmed.abn9074},
journal = {Science Translational Medicine},
pages = {1--17},
title = {Translating musculoskeletal bioengineering into tissue regeneration therapies.},
url = {http://dx.doi.org/10.1126/scitranslmed.abn9074},
volume = {14},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Musculoskeletal injuries and disorders are the leading cause of physical disability worldwide and a considerable socioeconomic burden. The lack of effective therapies has driven the development of novel bioengineering approaches that have recently started to gain clinical approvals. In this review, we first discuss the self-repair capacity of the musculoskeletal tissues and describe causes of musculoskeletal dysfunction. We then review the development of novel biomaterial, immunomodulatory, cellular, and gene therapies to treat musculoskeletal disorders. Last, we consider the recent regulatory changes and future areas of technological progress that can accelerate translation of these therapies to clinical practice.
AU - Khodabukus,A
AU - Guyer,T
AU - Moore,AC
AU - Stevens,MM
AU - Guldberg,RE
AU - Bursac,N
DO - 10.1126/scitranslmed.abn9074
EP - 17
PY - 2022///
SN - 1946-6234
SP - 1
TI - Translating musculoskeletal bioengineering into tissue regeneration therapies.
T2 - Science Translational Medicine
UR - http://dx.doi.org/10.1126/scitranslmed.abn9074
UR - https://www.ncbi.nlm.nih.gov/pubmed/36223445
UR - https://www.science.org/doi/10.1126/scitranslmed.abn9074
UR - http://hdl.handle.net/10044/1/100586
VL - 14
ER -