Imperial College London
Alternate

Professor Molly Stevens

Faculty of Engineering, Department of Materials

Professor of Biomedical Materials and Regenerative Medicine
 
 
 
//

Contact

 

+44 (0)20 7594 6804m.stevens

 
 
//

Location

 

208Royal School of MinesSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Fernandez-Galiana:2023:10.1002/adma.202210807,
author = {Fernandez-Galiana, A and Bibikova, O and Pedersen, S and Stevens, M},
doi = {10.1002/adma.202210807},
journal = {Advanced Materials},
title = {Fundamentals and applications of Raman-based techniques for the design and development of active biomedical materials},
url = {http://dx.doi.org/10.1002/adma.202210807},
year = {2023}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Raman spectroscopy is an analytical method based on light–matter interactions that can interrogate the vibrational modes of matter and provide representative molecular fingerprints. Mediated by its label-free, non-invasive nature, and high molecular specificity, Raman-based techniques have become ubiquitous tools for in situ characterization of materials. This review comprehensively describes the theoretical and practical background of Raman spectroscopy and its advanced variants. The numerous facets of material characterization that Raman scattering can reveal, including biomolecular identification, solid-to-solid phase transitions, and spatial mapping of biomolecular species in bioactive materials, are highlighted. The review illustrates the potential of these techniques in the context of active biomedical material design and development by highlighting representative studies from the literature. These studies cover the use of Raman spectroscopy for the characterization of both natural and synthetic biomaterials, including engineered tissue constructs, biopolymer systems, ceramics, and nanoparticle formulations, among others. To increase the accessibility and adoption of these techniques, the present review also provides the reader with practical recommendations on the integration of Raman techniques into the experimental laboratory toolbox. Finally, perspectives on how recent developments in plasmon- and coherently-enhanced Raman spectroscopy can propel Raman from underutilized to critical for biomaterial development are provided.
AU  - Fernandez-Galiana,A
AU  - Bibikova,O
AU  - Pedersen,S
AU  - Stevens,M
DO  - 10.1002/adma.202210807
PY  - 2023///
SN  - 0935-9648
TI  - Fundamentals and applications of Raman-based techniques for the design and development of active biomedical materials
T2  - Advanced Materials
UR  - http://dx.doi.org/10.1002/adma.202210807
UR  - http://hdl.handle.net/10044/1/107373
ER  -
Download