Imperial College London
Alternate

ProfessorMasaoTakata

Faculty of Medicine, Department of Surgery & Cancer

Magill Chair in Anaesthetics & Head of Division of APMIC
 
 
 
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Contact

 

+44 (0)20 3315 8816m.takata

 
 
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Location

 

G3.46Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Publication Type
Year
to

170 results found

Wakabayashi K, Wilson MR, O'Dea KP, Takata Met al., 2010, COMPARISON OF HIGH-STRETCH VERSUS ATELECTASIS IN THE PATHOPHYSIOLOGY OF VENTILATOR-INDUCED LUNG INJURY USING THE MOUSE ISOLATED PERFUSED LUNG, British-Thoracic-Society-Winter-Meeting 2010, Publisher: B M J PUBLISHING GROUP, Pages: A49-A50, ISSN: 0040-6376

Conference paper

Bertok S, Wilson MR, Morley PJ, de Wildt R, Bayliffe A, Takata Met al., 2010, SPECIFIC INHIBITION OF INTRA-ALVEOLAR P55 TNF RECEPTOR SIGNALLING BY A DOMAIN ANTIBODY ATTENUATES VENTILATOR-INDUCED LUNG INJURY IN MICE, 23rd Annual Meeting of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: S196-S196, ISSN: 0342-4642

Conference paper

Wilson MR, O'Dea KP, Dorr AD, Yamamoto H, Goddard ME, Takata Met al., 2010, Efficacy and safety of inhaled carbon monoxide during pulmonary inflammation in mice, PLOS One, Vol: 5, ISSN: 1932-6203

Journal article

Handy JM, Scott AJ, Cross AM, Sinha P, O'Dea KP, Takata Met al., 2010, HLA-DR expression and differential trafficking of monocyte subsets following low to intermediate risk surgery, ANAESTHESIA, Vol: 65, Pages: 27-35, ISSN: 0003-2409

Journal article

Patel BV, Wilson MR, Takata M, 2010, A physiologcal characterisation of injury, inflammation and resolution in murine aspiration pneumonitis., British-Thoracic-Society-Winter-Meeting, Pages: A183-A183

Conference paper

Cibelli M, Fidalgo AR, Terrando N, Ma D, Monaco C, Feldmann M, Takata M, Lever I, Nanchahal J, Fanselow M, Maze Met al., 2010, Role of Interleukin-1β in Postoperative Cognitive Dysfunction, Ann Neurol, Vol: 68, Pages: 360-368

Journal article

Dorr AD, Wilson MR, O'Dea KP, Takata Met al., 2009, SOURCES OF INCREASED PLASMA SOLUBLE TNF RECEPTORS DURING INJURIOUS MECHANICAL VENTILATION IN MICE, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A46-A47, ISSN: 0040-6376

Conference paper

Scott AJ, O'Dea KP, Handy JM, Takata Met al., 2009, ROS-DEPENDENT ACTIVATION OF P38 MAPK IS REQUIRED FOR LPS-INDUCED UPREGULATION OF TNFα-CONVERTING ENZYME (TACE/ADAM-17) ACTIVITY ON PRIMARY HUMAN MONOCYTES, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A47-A48, ISSN: 0040-6376

Conference paper

Dokpesi JO, O'Dea KP, Takata M, 2009, DIFFERENTIAL ACTIVATION OF THE P38 MAP KINASE PATHWAY IN MOUSE MONOCYTE SUBSETS DURING CO-CULTURE WITH PULMONARY ENDOTHELIAL CELLS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A49-A49, ISSN: 0040-6376

Conference paper

Wakabayashi K, Wilson MR, O'Dea KP, Takata Met al., 2009, ROLE OF INTRAVASCULAR LEUCOCYTES IN VENTILATOR-INDUCED LUNG INJURY IN THE ISOLATED PERFUSED MOUSE LUNG, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A48-A49, ISSN: 0040-6376

Conference paper

Fletcher M, Boshier P, Smolenski RT, Kirkham PA, Keun H, Hanna G, Takata M, Marczin Net al., 2009, MOLECULAR MECHANISMS OF LUNG EPITHELIAL CELL INJURY INDUCED BY INHIBITION OF GLUTATHIONE-<i>S</i>-TRANSFERASE, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A38-A39, ISSN: 0040-6376

Conference paper

Handy JM, Scott AJ, Cross AM, Sinha P, O'Dea KP, Takata Met al., 2009, LOW AND INTERMEDIATE RISK SURGERY INDUCES ACUTE DEPRESSION OF MONOCYTE HLA-DR EXPRESSION AND DYNAMIC TRAFFICKING OF MONOCYTE SUBSETS, 22nd Annual Congress of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: 274-274, ISSN: 0342-4642

Conference paper

Wilson MR, O'Dea KP, Zhang D, Shearman AD, van Rooijen N, Takata Met al., 2009, Role of Lung-marginated Monocytes in an <i>In Vivo</i> Mouse Model of Ventilator-induced Lung Injury, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, Pages: 914-922, ISSN: 1073-449X

Journal article

O'Dea KP, Wilson MR, Dokpesi JO, Wakabayashi K, Tatton L, van Rooijen N, Takata Met al., 2009, Mobilization and Margination of Bone Marrow Gr-1<SUP>high</SUP> Monocytes during Subclinical Endotoxemia Predisposes the Lungs toward Acute Injury, JOURNAL OF IMMUNOLOGY, Vol: 182, Pages: 1155-1166, ISSN: 0022-1767

Journal article

Alvarez-Iglesias M, Wayne G, O'Dea KP, Amour A, Takata Met al., 2009, Continuous real-time measurement of tumor necrosis factor-α converting enzyme activity on live cells (vol 85, pg 1440, 2005), LABORATORY INVESTIGATION, Vol: 89, Pages: 106-106, ISSN: 0023-6837

Journal article

Fletcher M, Takata M, Marczin N, 2009, Inhibitors of Glutathione-S-Transferase (GST) Induce Cell Death in Lung Epithelial Cells., Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Fletcher M, Takata M, Marczin N, 2009, Differential Sensitivity of Mouse (MLE) and Human (A549) Lung Alveolar Epithelial Cells to GST Inhibition and Oxidative Stress., Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Bertok S, Wilson MR, Dokpesi J, O'Dea KP, Marczin N, Takata Met al., 2009, Tumour Necrosis Factor-α (TNF) Receptor p75 Plays a Substantial Role in TNF-Mediated Upregulation of Leukocyte Adhesion Molecules in Mouse Lung Microvasculature, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Dorr AD, Wilson MR, Wakabayashi K, O'Dea KP, Takata Met al., 2009, Injurious Ventilation and Intratracheal Lipopolysaccharide Increase Soluble TNF Receptors in the Alveoli Via Distinct Mechanisms, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Scott AJ, Takata M, O'dea KP, 2008, REDOX MODIFICATION OF DITHIOLS/DISULPHIDES REGULATES TUMOUR NECROSIS FACTOR ALPHA-CONVERTING ENZYME ACTIVITY ON PRIMARY HUMAN MONOCYTES, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A141-A142, ISSN: 0040-6376

Conference paper

Dokpesi JO, O'Dea KP, Takata M, 2008, REGULATION OF MOUSE MONOCYTE TUMOUR NECROSIS FACTOR EXPRESSION BY PULMONARY ENDOTHELIAL CELLS IN VITRO, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A72-A73, ISSN: 0040-6376

Conference paper

Bertok S, Wilson MR, Dokpesi J, O'Dea KP, Marczin N, Takata Met al., 2008, ROLE OF TUMOUR NECROSIS FACTOR a RECEPTOR SUBTYPES IN TUMOUR NECROSIS FACTOR-INDUCED MOUSE LUNG MICROVASCULAR ENDOTHELIAL CELL ACTIVATION, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A141-A141, ISSN: 0040-6376

Conference paper

Dorr AD, Wilson MR, Wakabayashi K, O'Dea KP, Takata Met al., 2008, INJURIOUS VENTILATION AND INTRATRACHEAL LIPOPOLYSACCHARIDE INCREASE SOLUBLE TUMOUR NECROSIS FACTOR RECEPTORS IN THE ALVEOLI VIA TWO DISTINCT MECHANISMS, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A71-A71, ISSN: 0040-6376

Conference paper

Fletcher M, Takata M, Marczin N, 2008, INHIBITORS OF GLUTATHIONE-S-TRANSFERASE INDUCE CELL DEATH IN LUNG EPITHELIAL CELLS, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A144-A144, ISSN: 0040-6376

Conference paper

Waite AC, Wilson MR, Takata M, 2008, HIGH TIDAL VOLUME VENTILATION INDUCES RECRUITMENT OF ACTIVATED LEUCOCYTES TO EXTRAPULMONARY ORGANS IN AN IN-VIVO MOUSE MODEL, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A149-A149, ISSN: 0040-6376

Conference paper

Rippon HJ, Lane S, Qin M, Ismail N-S, Wilson MR, Takata M, Bishop AEet al., 2008, Embryonic stem cells as a source of pulmonary epithelium in vitro and in vivo., Proc Am Thorac Soc, Vol: 5, Pages: 717-722, ISSN: 1546-3222

Embryonic stem cells (ESCs) derived from the preimplantation blastocyst are pluripotent and capable of indefinite expansion in vitro. As such, they present a cell source to derive a potentially inexhaustible supply of pulmonary cells and tissue. ESC-derived pulmonary epithelium could be used for in vitro cell or tissue models or, in the future, implanted into the damaged or diseased lung to effect repair. Efforts to date have largely focused on obtaining distal lung epithelial phenotypes from ESCs, notably alveolar epithelium. Several disparate methods have been developed to enhance differentiation of ESCs into pulmonary epithelial lineages; these are broadly based on recapitulating developmental signaling events, mimicking the physical environment, or forcibly reprogramming the ESC nucleus. Early findings of our preclinical experiments implanting differentiated ESCs into the injured lung are also described here. Future efforts will focus on maximizing ESC differentiation efficiency and yield of the target phenotype, as well as characterizing the function of derived cells in vivo and in vitro.

Journal article

Brennan FM, Green P, Amjadi P, Robertshaw HJ, Alvarez-Iglesias M, Takata Met al., 2008, Interleukin-10 regulates TNF-α-converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 38, Pages: 1106-1117, ISSN: 0014-2980

Journal article

Pinhu L, Wilson M, Takata M, Griffiths Met al., 2007, Cyclo-oxygenase-2 induction by cyclic mechanical strain in human primary alveolar type 2 cells and in murine whole lung is dependent on activation of erk1/2, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A60-A61, ISSN: 0040-6376

Conference paper

Scott A, O'Dea KP, Smythe JF, Handy J, Takata Met al., 2007, Lipopolysaccharide-induced upregulation of tumour necrosis factor-alpha converting enzyme activity on primary human monocytes, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A114-A114, ISSN: 0040-6376

Conference paper

O'Dea KP, Wilson MR, Dokpesi JO, Takata Met al., 2007, Lung-marginated monocytes play a central role in a two-hit LPS-zymosan model of acute lung injury in mice, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A36-A37, ISSN: 0040-6376

Conference paper

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