@article{Goodwill:2001, author = {Goodwill, KE and Tennant, MG and Stevens, RC}, journal = {Drug Discovery Today}, title = {High-throughput x-ray crystallography for structure-based drug design}, volume = {6}, year = {2001} }
TY - JOUR AB - Knowledge of the 3D structure of proteins can play a key role in both understanding the biochemical function of protein targets, and developing small-molecule drugs that interact with these targets. This review will discuss recent advances in automation and miniaturization, which are making the determination of protein structures faster, more reliable, and more economical than has been possible historically. AU - Goodwill,KE AU - Tennant,MG AU - Stevens,RC PY - 2001/// SN - 1359-6446 TI - High-throughput x-ray crystallography for structure-based drug design T2 - Drug Discovery Today VL - 6 ER -