Imperial College London
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Dr Marcela P. Vizcaychipi

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 3315 8903m.vizcaychipi Website

 
 
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Location

 

3.21Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Morton:2021:10.1177/1751143720947547,
author = {Morton, S and Lamont, H and Silvey, N and Browning, T and Hayes, M and Keays, R and Christie, L and Davies, R and Singh, S and Lockie, C and Sisson, A and Vizcaychipi, M},
doi = {10.1177/1751143720947547},
journal = {Journal of the Intensive Care Society},
pages = {288--299},
title = {Adult intensive care unit admissions with severe COVID-19 infection following emergency Caesarean section deliveries: a case series},
url = {http://dx.doi.org/10.1177/1751143720947547},
volume = {22},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundUK data suggest 6% of COVID-19 hospital admissions are either currently pregnant or immediately post-partum. However, the current literature suggests that if COVID-19 occurs in pregnancy, or post-partum, symptoms are mostly mild.MethodsAll COVID-19 admissions to one acute London National Health Service Foundation trust were reviewed since the beginning of the COVID-19 pandemic to 1 May 2020 to establish whether there were any pregnant or immediately post-partum admissions. Data were extracted from hospital electronic records and anonymised. Any patients admitted to adult intensive care unit had their case notes reviewed in detail and comparison made to a local risk-assessment guideline identifying patients at-risk of thromboembolic events or cytokine storms. Local hospital guidelines were followed. Patients admitted to adult intensive care unit gave written consent.ResultsA total of 24 pregnant or immediately post-partum patients with COVID-19 were admitted. Three patients required long adult intensive care unit admissions for severe single-organ respiratory failure after emergency C-sections. Two of these patients required proning (three times and eight times, respectively). All were considered medium risk for thromboembolic events but had rising D-dimers following adult intensive care unit admission, resulting in increased dosing of pharmacological thromboprophylaxis throughout their admission. All were considered low risk for a cytokine storm, and none had any significant cardiovascular or renal involvement. One patient developed a super-imposed fungal lung infection. All three patients developed delirium following cessation of sedation.ConclusionPregnant or immediately post-partum women can develop severe COVID-19 symptoms requiring prolonged adult intensive care unit admission. It is likely to be single-organ failure, but patients are at a high risk of a thromboembolic event and delirium.
AU  - Morton,S
AU  - Lamont,H
AU  - Silvey,N
AU  - Browning,T
AU  - Hayes,M
AU  - Keays,R
AU  - Christie,L
AU  - Davies,R
AU  - Singh,S
AU  - Lockie,C
AU  - Sisson,A
AU  - Vizcaychipi,M
DO  - 10.1177/1751143720947547
EP  - 299
PY  - 2021///
SN  - 1751-1437
SP  - 288
TI  - Adult intensive care unit admissions with severe COVID-19 infection following emergency Caesarean section deliveries: a case series
T2  - Journal of the Intensive Care Society
UR  - http://dx.doi.org/10.1177/1751143720947547
UR  - https://journals.sagepub.com/doi/10.1177/1751143720947547
UR  - http://hdl.handle.net/10044/1/82585
VL  - 22
ER  -
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