Imperial College London

Dr Marcela P. Vizcaychipi

Faculty of MedicineDepartment of Surgery & Cancer

Honorary Clinical Senior Lecturer



+44 (0)20 3315 8903m.vizcaychipi Website




3.21Chelsea and Westminster HospitalChelsea and Westminster Campus




Recent Publications

1. Mapping the human genetic architecture of COVID-19.  COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. PMID: 34237774.

2. Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
Devereaux PJ, Marcucci M, Painter TW, Conen D, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Martínez-Zapata MJ, Wang CY, Xavier D, Ofori SN, Wang MK, Efremov S, Landoni G, Kleinlugtenbelt YV, Szczeklik W, Schmartz D, Garg AX, Short TG, Wittmann M, Meyhoff CS, Amir M, Torres D, Patel A, Duceppe E, Ruetzler K, Parlow JL, Tandon V, Fleischmann E, Polanczyk CA, Lamy A, Astrakov SV, Rao M, Wu WKK, Bhatt K, de Nadal M, Likhvantsev VV, Paniagua P, Aguado HJ, Whitlock RP, McGillion MH, Prystajecky M, Vincent J, Eikelboom J, Copland I, Balasubramanian K, Turan A, Bangdiwala SI, Stillo D, Gross PL, Cafaro T, Alfonsi P, Roshanov PS, Belley-Côté EP, Spence J, Richards T, VanHelder T, McIntyre W, Guyatt G, Yusuf S, Leslie K; POISE-3 Investigators. N Engl J Med. 2022 May 26;386(21):1986-1997. doi: 10.1056/NEJMoa2201171. Epub 2022 Apr 2. PMID: 35363452 Clinical Trial.

3. Continuous Non-Invasive Eye Tracking In Intensive Care.
Al-Hindawi A, Vizcaychipi MP, Demiris Y. Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:1869-1873. doi: 10.1109/EMBC46164.2021.9630999.
PMID: 34891652.

4. Vitamin D: The 'Immune Cell Mediator' in burn critical care patients.
Shida A, Vizcaychipi M. Burns. 2021 Aug;47(5):1216-1217. doi: 10.1016/j.burns.2021.02.002. Epub 2021 Feb 17. PMID: 33840552.

5. Management and outcomes in critically ill nonagenarian versus octogenarian patients. Bruno RR, Wernly B, Kelm M, Boumendil A, Morandi A, Andersen FH, Artigas A, Finazzi S, Cecconi M, Christensen S, Faraldi L, Lichtenauer M, Muessig JM, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Leaver S, Boulanger C, Walther S, Schefold JC, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Zafeiridis T, De Lange DW, Guidet B, Flaatten H, Jung C; VIP2 study group.
BMC Geriatr. 2021 Oct 19;21(1):576. doi: 10.1186/s12877-021-02476-4.
PMID: 34666709.

6.Vitamin C Intervention for Critical COVID-19: A Pragmatic Review of the Current Level of Evidence. Holford P, Carr AC, Zawari M, Vizcaychipi MP.
Life (Basel). 2021 Nov 1;11(11):1166. doi: 10.3390/life11111166. PMID: 34833042.

7. Inflammation Disrupts the Brain Network of Executive Function After Cardiac Surgery. Zhu Y, Zhou M, Jia X, Zhang W, Shi Y, Bai S, Rampes S, Vizcaychipi MP, Wu C, Wang K, Ma D, Yang Q, Wang L. Ann Surg. 2021 Jul 2. doi: 10.1097/SLA.0000000000005041. Online ahead of print.
PMID: 34225294.

8.Lactate dehydrogenase activity staining demonstrates time-dependent immune cell infiltration in human ex-vivo burn-injured skin.
Cuddihy J, Wu G, Ho L, Kudo H, Dannhorn A, Mandalia S, Collins D, Weir J, Spencer A, Vizcaychipi M, Takats Z, Nagy I. Sci Rep. 2021 Oct 28;11(1):21249. doi: 10.1038/s41598-021-00644-5. PMID: 34711882.

9. Prognosis and antibody profiles in survivors of critical illness from COVID-19: a prospective multicentre cohort study. Yang X, Li Z, Wang B, Pan Y, Jiang C, Zhang X, Yang Y, Zhou C, Hu C, Zhang Z, Xu H, Liao W, Vizcaychipi MP, Sanders RD, Li Y, Ma D, Peng Z. Br J Anaesth. 2022 Mar;128(3):491-500. doi: 10.1016/j.bja.2021.11.024. Epub 2021 Nov 26. PMID: 34980470.

10.Histological findings of tracheal samples from COVID-19 positive critically ill mechanically ventilated patients. Ward PA, Collier JM, Weir J, Osborn M, Hanley B, Smellie WJB; Chelwest COVID-19 Tracheostomy Group. Clin Otolaryngol. 2022 Jan;47(1):131-137. doi: 10.1111/coa.13872. Epub 2021 Oct 18.
PMID: 34606150.

11. Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. STARRT-AKI Investigators; Canadian Critical Care Trials Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group, the United Kingdom Critical Care Research Group, the Canadian Nephrology Trials Network, and the Irish Critical Care Trials Group; Engl J Med. 2020 Jul 16;383(3):240-251.  doi: 10.1056/NEJMoa2000741.

12. The iCareWean protocol on weaning from mechanical ventilation: A Single-blinded multi-centre randomised control trial comparing an open-loop decision support system and routine care, in the general Intensive Care Unit. BMJ Open. Accepted on 8th July 2020. bmjopen-2020-042145.R1

13. Adult Intensive Care Unit (AICU) admissions with severe COVID-19 infection following emergency Caesarean section deliveries: A case series. Journal of Intensive Care Medicine. Accepted on 19th June 2020. INC-20-0103.

14. Implications for COVID-19 triage from the ICNARC report of 2204 COVID-19 cases managed in UK adult intensive care units. Emergency Medicine Journal. 2020-06. DOI: 10.1136/emermed-2020-209791

15. COVID-19 genomic susceptibility: Definition of ACE2 variants relevant to human infection with SARS-CoV-2 in the context of ACMG/AMP Guidance2020-05-18 | other. DOI: 10.1101/2020.05.12.20098160

16. Early detection of severe COVID-19 disease patterns define near real-time personalised care, bioseverity in males, and decelerating mortality rates.2020-05-11 DOI: 10.1101/2020.05.08.2008839

17. Let's not forget our female front line. BMJ (Clinical research ed.) 2020. DOI: 10.1136/bmj.m2167EID: 2-s2.0-85085908757Part of ISBN: 17561833

18. The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study Intensive Care Medicine 2020. DOI: 10.1007/s00134-019-05853-1EID: 2-s2.0

19. Risk factors for clinical progression in patients with COVID-19: a retrospective study of electronic health record data in the United Kingdom. medRxiv 2020.05.11.20093096; doi:

 20. COVID-19 in London, a Case Series Demonstrating Late Improvement in Survivors. medRxiv 2020.05.16.20103853; doi:

21. Early risk assessment for COVID-19 patients from emergency department data using machine learning. medRxiv 2020.05.19.20086488; doi:

22. Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) with Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial. JAMA - Journal of the American Medical Association 2019. DOI: 10.1001/jama.2019.7505

23.  Non-invasive real-time autonomic function characterization during surgery via continuous Poincaré quantification of heart rate variability. J Clin Monit Comput. 2018 Oct 3. doi: 10.1007/s10877-018-0206-4. 2.

24. Attribution bias underlying burns-induced anxiety symptoms. Burns. 2018 Sep;44(6):1502-1508. doi: 10.1016/j.burns.2018.05.004. Epub 2018 Jun 7.

25. Perioperative Research into Memory (PRiMe): Cognitive impairment following a severe burn injury and critical care admission, part 1. Burns. 2018 Aug;44(5):1167-1178. doi: 10.1016/j.burns.2018.04.011.

26. Scoping review on the use of socially assistive robot technology in elderly care. BMJ Open. 2018 Feb 12;8(2):e018815. doi: 10.1136/bmjopen-2017-018815. Review.

Snapshot of MPV's Research Team

MPV Research Group 

Higher Education

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PhD (Imperial College London) 2012

 FFICM (Fellow Faculty of Intensive Care Medicine) 2011

 FRCA (Fellow Royal College of Anaesthetists) 2003

 MD (University of Buenos Aires, Argentina) 1997

 MBBS (University of the North East, Argentina) 1994

 BSc in Physiology with Basic Medical Sciences (University of North East, Argentina) 2:1 1990

Membership of Professional Bodies, Learned Societies etc

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European Society of Anaesthesiology & Intensive Care Medicine since 2019.

Faculty of Clinical Informatics since 2018.

British Burn Association since 2015 and European Society of Burn 2015.

General Medical Council (5206130) Specialist Register, Anaesthesia and Intensive Care Medicine since May 2009.

Association of Anaesthetists of Great Britain and Ireland since 2005.

Society of Critical Care Medicine since 2001.

British Medical Association since 2000.

Intensive Care Society (ICS) since 2000.

European Society of Intensive Care Medicine since 1999.

General Medical Council (5206130) since 2002.