Imperial College London
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Professor Mark Wilson

Faculty of Medicine, Department of Surgery & Cancer

Professor of Practice
 
 
 
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Contact

 

+44 (0)20 7594 1532m.wilson

 
 
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Location

 

Cambridge WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Garara:2016:10.1016/j.injury.2015.12.020,
author = {Garara, B and Wood, A and Marcus, HJ and Tsang, K and Wilson, MH and Khan, M},
doi = {10.1016/j.injury.2015.12.020},
journal = {Injury},
pages = {539--544},
title = {INTRAMUSCULAR DIAPHRAGMATIC STIMULATION FOR PATIENTS WITH TRAUMATIC HIGH CERVICAL INJURIES AND VENTILATOR DEPENDENT RESPIRATORY FAILURE: A SYSTEMATIC REVIEW OF SAFETY AND EFFECTIVENESS},
url = {http://dx.doi.org/10.1016/j.injury.2015.12.020},
volume = {47},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundIntramuscular diaphragmatic stimulation using an abdominal laparoscopic approach has been proposed as a safer alternative to traditional phrenic nerve stimulation. It has also been suggested that early implementation of diaphragmatic pacing may prevent diaphragm atrophy and lead to earlier ventilator independence. The aim of this study was therefore to systematically review the safety and effectiveness of intramuscular diaphragmatic stimulators in the treatment of patients with traumatic high cervical injuries resulting in long-term ventilator dependence, with particular emphasis on the affect of timing of insertion of such stimulators.MethodsThe Cochrane database and PubMed were searched between January 2000 and June 2015. Reference lists of selected papers were also reviewed. The inclusion criteria used to select from the pool of eligible studies were: (1) reported on adult patients with traumatic high cervical injury, who were ventilator-dependant, (2) patients underwent intramuscular diaphragmatic stimulation, and (3) commented on safety and/or effectiveness.Results12 articles were included in the review. Reported safety issues post insertion of intramuscular electrodes included pneumothorax, infection, and interaction with pre-existing cardiac pacemaker. Only one procedural failure was reported. The percentage of patients reported as independent of ventilatory support post procedure ranged between 40% and 72.2%. The mean delay of insertion ranged from 40 days to 9.7 years; of note the study with the average shortest delay in insertion reported the greatest percentage of fully weaned patients.ConclusionsAlthough evidence for intramuscular diaphragmatic stimulation in patients with high cervical injuries and ventilator dependent respiratory failure is currently limited, the technique appears to be safe and effective. Earlier implantation of such devices does not appear to be associated with greater surgical risk, and may be more effective. Further high
AU  - Garara,B
AU  - Wood,A
AU  - Marcus,HJ
AU  - Tsang,K
AU  - Wilson,MH
AU  - Khan,M
DO  - 10.1016/j.injury.2015.12.020
EP  - 544
PY  - 2016///
SN  - 0020-1383
SP  - 539
TI  - INTRAMUSCULAR DIAPHRAGMATIC STIMULATION FOR PATIENTS WITH TRAUMATIC HIGH CERVICAL INJURIES AND VENTILATOR DEPENDENT RESPIRATORY FAILURE: A SYSTEMATIC REVIEW OF SAFETY AND EFFECTIVENESS
T2  - Injury
UR  - http://dx.doi.org/10.1016/j.injury.2015.12.020
VL  - 47
ER  -
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