Imperial College London

ProfessorMajidEzzati

Faculty of MedicineSchool of Public Health

Chair in Global Environmental Health
 
 
 
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Contact

 

+44 (0)20 7594 0767majid.ezzati Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Brehmer:2019:10.1021/acs.est.8b05120,
author = {Brehmer, C and Lai, A and Clark, S and Shan, M and Ni, K and Ezzati, M and Yang, X and Baumgartner, J and Schauer, JJ and Carter, E},
doi = {10.1021/acs.est.8b05120},
journal = {Environmental Science and Technology},
pages = {2788--2798},
title = {The oxidative potential of personal and household PM2.5 in a rural setting in southwestern China},
url = {http://dx.doi.org/10.1021/acs.est.8b05120},
volume = {53},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The chemical constituents of fine particulate matter (PM2.5) vary by source and capacity to participate in redox reactions in the body, which produce cytotoxic reactive oxygen species (ROS). Knowledge of the sources and components of PM2.5 may provide insight into the adverse health effects associated with the inhalation of PM2.5 mass. We collected 48 h household and personal PM2.5 exposure measurements in the summer months among 50 women/household pairs in a rural area of southwestern China where daily household biomass burning is common. PM2.5 mass was analyzed for ions, trace metals, black carbon, and water-soluble organic matter, as well as ROS-generating capability (oxidative potential) by one cellular and one acellular assay. Crustal enrichment factors and a principal component analysis identified the major sources of PM2.5 as dust, biomass burning, and secondary sulfate. Elements associated with the secondary sulfate source (As, Mo, Zn) had the strongest correlation with increased cellular oxidative potential (Spearman r: 0.74, 0.68, and 0.64). Chemical markers of biomass burning (water-soluble potassium and water-soluble organic matter) had negligible oxidative potential, suggesting that these assays may not be useful as health-relevant exposure metrics in populations that are exposed to high levels of smoke from household biomass burning.
AU - Brehmer,C
AU - Lai,A
AU - Clark,S
AU - Shan,M
AU - Ni,K
AU - Ezzati,M
AU - Yang,X
AU - Baumgartner,J
AU - Schauer,JJ
AU - Carter,E
DO - 10.1021/acs.est.8b05120
EP - 2798
PY - 2019///
SN - 0013-936X
SP - 2788
TI - The oxidative potential of personal and household PM2.5 in a rural setting in southwestern China
T2 - Environmental Science and Technology
UR - http://dx.doi.org/10.1021/acs.est.8b05120
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000460709100055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/68799
VL - 53
ER -