Imperial College London

ProfessorMajidEzzati

Faculty of MedicineSchool of Public Health

Chair in Global Environmental Health
 
 
 
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Contact

 

+44 (0)20 7594 0767majid.ezzati Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sampson:2014:10.1016/j.gheart.2013.12.010,
author = {Sampson, UKA and Norman, PE and Fowkes, FGR and Aboyans, V and Yanna, Song and Harrell, FE and Forouzanfar, MH and Naghavi, M and Denenberg, JO and McDermott, MM and Criqui, MH and Mensah, GA and Ezzati, M and Murray, C},
doi = {10.1016/j.gheart.2013.12.010},
journal = {Glob Heart},
pages = {171--180.e10},
title = {Global and regional burden of aortic dissection and aneurysms: mortality trends in 21 world regions, 1990 to 2010.},
url = {http://dx.doi.org/10.1016/j.gheart.2013.12.010},
volume = {9},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A comprehensive and systematic assessment of the global burden of aortic aneurysms (AA) has been lacking. Therefore, we estimated AA regional deaths and years of life lost (YLL) in 21 regions worldwide for 1990 and 2010. We used the GBD (Global Burden of Disease) 2010 study causes of death database and the cause of death ensemble modeling approach to assess levels and trends of AA deaths by age, sex, and GBD region. The global AA death rate per 100,000 population was 2.49 (95% CI: 1.78 to 3.27) in 1990 and 2.78 (95% CI: 2.04 to 3.62) in 2010. In 1990 and 2010, the highest mean death rates were in Australasia and Western Europe: 8.82 (95% CI: 6.96 to 10.79) and 7.69 (95% CI: 6.11 to 9.57) in 1990 and 8.38 (95% CI: 6.48 to 10.86) and 7.68 (95% CI: 6.13 to 9.54) in 2010. YLL rates by GBD region mirrored the mortality rate pattern. Overall, men had higher AA death rates than women: 2.86 (95% CI: 1.90 to 4.22) versus 2.12 (95% CI: 1.33 to 3.00) in 1990 and 3.40 (95% CI: 2.26 to 5.01) versus 2.15 (95% CI: 1.44 to 2.89) in 2010. The relative change in median death rate was +0.22 (95% CI: 0.10 to 0.33) in developed nations versus +0.71 (95% CI: 0.28 to 1.40) in developing nations. The smallest relative changes in median death rate were noted in North America high income, Central Europe, Western Europe, and Australasia, with estimates of +0.07 (95% CI: -0.26 to 0.37), +0.08 (95% CI: -0.02 to 0.23), +0.09 (95% CI: -0.02 to 0.21), and +0.22 (95% CI: -0.08 to 0.46), respectively. The largest increases were in Asia Pacific high income, Southeast Asia, Latin America tropical, Oceania, South Asia, and Central Sub-Saharan Africa. Women rather than men drove the increase in the Asia Pacific high-income region: the relative change in median rates was +2.92 (95% CI: 0.6 to 4.35) versus +1.05 (95% CI: 0.61 to 2.42). In contrast to high-income regions, the observed pattern in developing regions suggests increasing AA burden, wh
AU - Sampson,UKA
AU - Norman,PE
AU - Fowkes,FGR
AU - Aboyans,V
AU - Yanna,Song
AU - Harrell,FE
AU - Forouzanfar,MH
AU - Naghavi,M
AU - Denenberg,JO
AU - McDermott,MM
AU - Criqui,MH
AU - Mensah,GA
AU - Ezzati,M
AU - Murray,C
DO - 10.1016/j.gheart.2013.12.010
EP - 180
PY - 2014///
SP - 171
TI - Global and regional burden of aortic dissection and aneurysms: mortality trends in 21 world regions, 1990 to 2010.
T2 - Glob Heart
UR - http://dx.doi.org/10.1016/j.gheart.2013.12.010
UR - https://www.ncbi.nlm.nih.gov/pubmed/25432126
VL - 9
ER -