Imperial College London

ProfessorMajidEzzati

Faculty of MedicineSchool of Public Health

Chair in Global Environmental Health
 
 
 
//

Contact

 

+44 (0)20 7594 0767majid.ezzati Website

 
 
//

Location

 

Norfolk PlaceSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Sampson:2014:10.1016/j.gheart.2013.12.008,
author = {Sampson, UKA and Fowkes, FGR and McDermott, MM and Criqui, MH and Aboyans, V and Norman, PE and Forouzanfar, MH and Naghavi, M and Song, Y and Harrell, FE and Denenberg, JO and Mensah, GA and Ezzati, M and Murray, C},
doi = {10.1016/j.gheart.2013.12.008},
journal = {Glob Heart},
pages = {145--158.e21},
title = {Global and regional burden of death and disability from peripheral artery disease: 21 world regions, 1990 to 2010.},
url = {http://dx.doi.org/10.1016/j.gheart.2013.12.008},
volume = {9},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A comprehensive and systematic assessment of disability and mortality due to lower extremity peripheral artery disease (PAD) is lacking. Therefore, we estimated PAD deaths, disability-adjusted life years (DALYs), and years of life lost in 21 regions worldwide for 1990 and 2010. We used the GBD (Global Burden of Diseases 2010) study causes of death database, and the cause of death ensemble modeling approach to assess levels and trends of PAD deaths and years of life lost over time, by age, sex, and region. Assessment of DALYs employed estimates of PAD prevalence from systematic reviews of epidemiologic data using a Bayesian meta-regression method. In 1990, the age-specific PAD death rate per 100,000 population ranged from 0.05 (95% confidence interval [CI]: 0.03 to 0.09) among those 40 to 44 years old to 16.63 (95% CI: 10.47 to 25.31) among the 80+ years group. In 2010, the corresponding estimates were 0.07 (95% CI: 0.04 to 0.13) and 28.71 (95% CI: 18.3 to 43.06). Death rates increased consistently with age in 1990 and 2010, and the rates in 2010 were higher than they were in 1990 in all age categories. The largest relative change in median death rate of +6.03 per 100,000 (95% CI: 1.50 to 11.85) was noted in the Asia Pacific-High Income region and was largely driven by higher rates in women: +17.36 (95% CI: 1.79 to 32.01) versus +1.25 (95% CI: 0.13 to 2.39) in men. The overall relative change in median DALYs was larger in developing nations than in developed nations: 1.15 (95% CI: 0.80 to 1.66) versus 0.77 (95% CI: 0.55 to 1.08). Of note, the overall relative change in median DALYs was higher among both men and women in developing versus developed countries: men: 1.18 (95% CI: 0.82 to 1.65) versus 0.51 (95% CI: 0.30 to 0.81), and women: 1.11 (95% CI: 0.58 to 2.02) versus 1 (95% CI: 0.67 to 1.47). Within developed nations, the overall relative change in median DALY rates was larger in women than in men: +1.00 (95% CI: 0.67 to 1.47) versus +0.5
AU - Sampson,UKA
AU - Fowkes,FGR
AU - McDermott,MM
AU - Criqui,MH
AU - Aboyans,V
AU - Norman,PE
AU - Forouzanfar,MH
AU - Naghavi,M
AU - Song,Y
AU - Harrell,FE
AU - Denenberg,JO
AU - Mensah,GA
AU - Ezzati,M
AU - Murray,C
DO - 10.1016/j.gheart.2013.12.008
EP - 158
PY - 2014///
SP - 145
TI - Global and regional burden of death and disability from peripheral artery disease: 21 world regions, 1990 to 2010.
T2 - Glob Heart
UR - http://dx.doi.org/10.1016/j.gheart.2013.12.008
UR - https://www.ncbi.nlm.nih.gov/pubmed/25432124
VL - 9
ER -