Imperial College London
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DrMariaPapathanasiou

Faculty of Engineering, Department of Chemical Engineering

Senior Lecturer
 
 
 
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Contact

 

maria.papathanasiou11

 
 
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Location

 

RODH.501DRoderic Hill BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sarkis:2021:10.3390/pr9030457,
author = {Sarkis, M and Bernardi, A and Shah, N and Papathanasiou, MM},
doi = {10.3390/pr9030457},
journal = {Processes},
pages = {1--16},
title = {Emerging challenges and opportunities in pharmaceutical manufacturing and distribution},
url = {http://dx.doi.org/10.3390/pr9030457},
volume = {9},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The rise of personalised and highly complex drug product profiles necessitates significant advancements in pharmaceutical manufacturing and distribution. Efforts to develop more agile, responsive, and reproducible manufacturing processes are being combined with the application of digital tools for seamless communication between process units, plants, and distribution nodes. In this paper, we discuss how novel therapeutics of high-specificity and sensitive nature are reshaping well-established paradigms in the pharmaceutical industry. We present an overview of recent research directions in pharmaceutical manufacturing and supply chain design and operations. We discuss topical challenges and opportunities related to small molecules and biologics, dividing the latter into patient- and non-specific. Lastly, we present the role of process systems engineering in generating decision-making tools to assist manufacturing and distribution strategies in the pharmaceutical sector and ultimately embrace the benefits of digitalised operations.
AU  - Sarkis,M
AU  - Bernardi,A
AU  - Shah,N
AU  - Papathanasiou,MM
DO  - 10.3390/pr9030457
EP  - 16
PY  - 2021///
SN  - 2227-9717
SP  - 1
TI  - Emerging challenges and opportunities in pharmaceutical manufacturing and distribution
T2  - Processes
UR  - http://dx.doi.org/10.3390/pr9030457
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000634249400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.mdpi.com/2227-9717/9/3/457
UR  - http://hdl.handle.net/10044/1/90499
VL  - 9
ER  -
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