Imperial College London
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DrMariaPapathanasiou

Faculty of Engineering, Department of Chemical Engineering

Senior Lecturer
 
 
 
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Contact

 

maria.papathanasiou11

 
 
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Location

 

RODH.501DRoderic Hill BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Triantafyllou:2022:10.1038/s41598-022-21290-5,
author = {Triantafyllou, N and Bernardi, A and Lakelin, M and Shah, N and Papathanasiou, M},
doi = {10.1038/s41598-022-21290-5},
journal = {Scientific Reports},
title = {A digital platform for the design of patient-centric supply chains},
url = {http://dx.doi.org/10.1038/s41598-022-21290-5},
volume = {12},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Chimeric Antigen Receptor (CAR) T cell therapies have received increasing attention, showing promising results in the treatment of acute lymphoblastic leukaemia and aggressive B cell lymphoma. Unlike typical cancer treatments, autologous CAR T cell therapies are patient-specific; this makes them a unique therapeutic to manufacture and distribute. In this work, we focus on the development of a computer modelling tool to assist the design and assessment of supply chain structures that can reliably and cost-efficiently deliver autologous CAR T cell therapies. We focus on four demand scales (200, 500, 1000 and 2000 patients annually) and we assess the tool’s capabilities with respect to the design of responsive supply chain candidate solutions while minimising cost.
AU  - Triantafyllou,N
AU  - Bernardi,A
AU  - Lakelin,M
AU  - Shah,N
AU  - Papathanasiou,M
DO  - 10.1038/s41598-022-21290-5
PY  - 2022///
SN  - 2045-2322
TI  - A digital platform for the design of patient-centric supply chains
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/s41598-022-21290-5
UR  - http://hdl.handle.net/10044/1/100178
VL  - 12
ER  -
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