Imperial College London
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DrMariaPapathanasiou

Faculty of Engineering, Department of Chemical Engineering

Senior Lecturer
 
 
 
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Contact

 

maria.papathanasiou11

 
 
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Location

 

RODH.501DRoderic Hill BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Papathanasiou:2015,
author = {Papathanasiou, MM and Campano, AQ and Steinebach, F and Mueller-Spaeth, T and Morbidelli, M and Mantalaris, A and Pistikopoulos, EN},
pages = {714--716},
title = {Advanced control strategies towards the intensification of monoclonal antibody production},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - CPAPER
AB  - Process intensification plays a dominant role in the improvement of sustainability and productivity of biopharmaceutical processes. In particular, during the past few years there has been increasing demand on product quality and higher titers in the production of monoclonal antibodies (mAbs) [1]. The latter consists of two main parts: (1) the upstream processing (USP), where the cells are cultured and the therapeutic agent is produced and (2) the downstream processing (DSP) that involves the isolation/purification of the targeted product. Both the upstream and the downstream processing, however, are affected by various parameters related to the design of the bioreactor, the methods chosen for separation/purification as well as the operation mode (e.g. batch or continuous).
AU  - Papathanasiou,MM
AU  - Campano,AQ
AU  - Steinebach,F
AU  - Mueller-Spaeth,T
AU  - Morbidelli,M
AU  - Mantalaris,A
AU  - Pistikopoulos,EN
EP  - 716
PY  - 2015///
SP  - 714
TI  - Advanced control strategies towards the intensification of monoclonal antibody production
ER  -
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