Imperial College London

Professor Matthew Fisher

Faculty of MedicineSchool of Public Health

Professor of Fungal Disease Epidemiology
 
 
 
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Contact

 

matthew.fisher Website

 
 
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Location

 

1113Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Fisher:2018:10.1126/science.aap7999,
author = {Fisher, MC and Hawkins, NJ and Sanglard, D and Gurr, SJ},
doi = {10.1126/science.aap7999},
journal = {Science},
pages = {739--742},
title = {Worldwide emergence of resistance to antifungal drugs challenges human health and food security},
url = {http://dx.doi.org/10.1126/science.aap7999},
volume = {360},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The recent rate of emergence of pathogenic fungi that are resistant to the limited number of commonly used antifungal agents is unprecedented. The azoles, for example, are used not only for human and animal health care and crop protection but also in antifouling coatings and timber preservation. The ubiquity and multiple uses of azoles have hastened the independent evolution of resistance in many environments. One consequence is an increasing risk in human health care from naturally occurring opportunistic fungal pathogens that have acquired resistance to this broad class of chemicals. To avoid a global collapse in our ability to control fungal infections and to avoid critical failures in medicine and food security, we must improve our stewardship of extant chemicals, promote new antifungal discovery, and leverage emerging technologies for alternative solutions.
AU - Fisher,MC
AU - Hawkins,NJ
AU - Sanglard,D
AU - Gurr,SJ
DO - 10.1126/science.aap7999
EP - 742
PY - 2018///
SN - 0036-8075
SP - 739
TI - Worldwide emergence of resistance to antifungal drugs challenges human health and food security
T2 - Science
UR - http://dx.doi.org/10.1126/science.aap7999
UR - https://www.ncbi.nlm.nih.gov/pubmed/29773744
UR - http://hdl.handle.net/10044/1/59856
VL - 360
ER -