Imperial College London

DrMatthewForeman

Faculty of Natural SciencesDepartment of Physics

Academic Visitor
 
 
 
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Contact

 

+44 (0)20 7594 7721matthew.foreman Website

 
 
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Location

 

642Blackett LaboratorySouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Urban:2018:10.1021/acsphotonics.7b00833,
author = {Urban, NT and Foreman, MR and Hell, SW and Sivan, Y},
doi = {10.1021/acsphotonics.7b00833},
journal = {ACS Photonics},
pages = {2574--2583},
title = {Nanoparticle-assisted STED nanoscopy with gold nanospheres},
url = {http://dx.doi.org/10.1021/acsphotonics.7b00833},
volume = {5},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - We demonstrate stimulated emission depletion (STED) microscopy with 20 nmgold nanospheres coated by fluorescent silica. Compared with previousdemonstrations of STED with a hybrid plasmonic fluorescent label, the currentimplementation offers a substantially smaller label and a better resolutionimprovement of up to 2.5-fold beyond the diffraction limit of confocalmicroscopy. This is achieved at approximately 2 times lower intensity thanconventional STED based on dyes alone, and in an aqueous environment,demonstrating the relevance to bio-imaging. Finally, we also show, for thefirst time in this context, a 3-fold reduction in the rate of photobleachingcompared to standard dye-based STED, thus, enabling brighter images.
AU - Urban,NT
AU - Foreman,MR
AU - Hell,SW
AU - Sivan,Y
DO - 10.1021/acsphotonics.7b00833
EP - 2583
PY - 2018///
SN - 2330-4022
SP - 2574
TI - Nanoparticle-assisted STED nanoscopy with gold nanospheres
T2 - ACS Photonics
UR - http://dx.doi.org/10.1021/acsphotonics.7b00833
UR - http://arxiv.org/abs/1611.00045v1
UR - http://hdl.handle.net/10044/1/54805
VL - 5
ER -