Imperial College London


Faculty of MedicineDepartment of Surgery & Cancer

Honorary Senior Research Fellow



+44 (0)20 3311 0733matthew.williams Website CV




Charing Cross HospitalCharing Cross Campus





I lead the Computational Oncology group at Imperial College, based jointly between the Dept. of Computing and Division of Surgery & Cancer.

We are interested in mathematical and computational approaches to clinical problems, including the use of machine learning, computational argumentation and the use of clinical 'big data'. In particular, we are interested in improving access to and use of clinical data, with the aim of developing and applying computational techniques to these data.

We talk about our work on the lab blog. I currently supervise 5 PhD/ MD students, as well as MRes & MSc student projects. We are open to supervising UG student projects, but would encourage students to apply through schemes such as the RCR SURF program.

I have held several local & national positions. I was previously Clinical Lead for QA at NCRAS and a Macmillan Advisor on Cancer data. I currently chair the RCR QI & Audit committee for clinical oncology. I am on the PC for IEEE CBMS

Clinically, I deliver radiotherapy and chemotherapy to patient with brain and spinal tumours, including IMRT and stereotactic radiotherapy. My clinical work is based at Charing Cross hospital, and we have a strong clinical-research link, including the BrainWear trial.

Significant previous & current work includes the Simulacrum and GlioCova.



Wang JW, Williams M, 2021, Exploring definitions of radiological sarcopenia in cancer: a protocol for a scoping review, Bmj Open, Vol:11, ISSN:2044-6055

Varughese M, Treece S, Drinkwater K, et al., 2021, Failing to Close the Gap between Evidence and Clinical Practice in Radical Bladder Cancer Radiotherapy: A Critical Unmet Need, Clinical Oncology, Vol:33, ISSN:0936-6555, Pages:340-341

Williams M, Mi E, Le Calvez K, et al., 2021, Estimating the risk of death from COVID-19 in adult cancer patients, Clinical Oncology, Vol:33, ISSN:0936-6555, Pages:e172-e79

Loveday C, Sud A, Jones ME, et al., 2020, Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study, Gut, Vol:70, ISSN:0017-5749, Pages:1053-1060


Spencer K, Hall P, Henry A, et al., 2020, Fractionation and early mortality in palliative radiotherapy across the English NHS, ELSEVIER IRELAND LTD, Pages:S285-S286, ISSN:0167-8140

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