Imperial College London
Alternate

ProfessorMarie-ClaudeBoily

Faculty of Medicine, School of Public Health

Professor of Mathematical Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 3263mc.boily

 
 
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Location

 

LG26Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@unpublished{Xia:2020:10.1101/2020.09.16.20196105,
author = {Xia, Y and Milwid, R and Godin, A and Boily, M-C and Johnson, L and Marsh, K and Eaton, J and Maheu-Giroux, M},
doi = {10.1101/2020.09.16.20196105},
title = {Accuracy of self-reported HIV testing history and awareness of HIV-positive status among people living with HIV in four Sub-Saharan African countries},
url = {http://dx.doi.org/10.1101/2020.09.16.20196105},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - UNPB
AB  - Background: In many countries in Sub-Saharan Africa, self-reported HIV testing history and awareness of HIV-positive status from household surveys are used to estimate the percentage of people living with HIV (PLHIV) who know their HIV status. Despite widespread use, there is limited empirical information on the sensitivity of those self-reports, which can be affected by non-disclosure. Methods: Bayesian latent class models were used to estimate the sensitivity of self-reported HIV testing history and awareness of HIV-positive status in four Population-based HIV Impact Assessment surveys in Eswatini, Malawi, Tanzania, and Zambia. Antiretroviral (ARV) metabolites biomarkers were used to identify persons on treatment who did not accurately report their status. For those without ARV biomarkers, the pooled estimate of non-disclosure among untreated persons was 1.48 higher than those on treatment. Results: Among PLHIV, the sensitivity of self-reported HIV testing history ranged 96% to 99% across surveys. Sensitivity of self-reported awareness of HIV status varied from 91% to 97%. Non-disclosure was generally higher among men and those aged 15-24 years. Adjustments for imperfect sensitivity did not substantially influence estimates of of PLHIV ever tested (difference <4%) but the proportion of PLHIV aware of their HIV-positive status was higher than the unadjusted proportion (difference <8%). Conclusions: Self-reported HIV testing histories in four Eastern and Southern African countries are generally robust although adjustment for non-disclosure increases estimated awareness of status. These findings can contribute to further refinements in methods for monitoring progress along the HIV testing and treatment cascade.
AU  - Xia,Y
AU  - Milwid,R
AU  - Godin,A
AU  - Boily,M-C
AU  - Johnson,L
AU  - Marsh,K
AU  - Eaton,J
AU  - Maheu-Giroux,M
DO  - 10.1101/2020.09.16.20196105
PY  - 2020///
TI  - Accuracy of self-reported HIV testing history and awareness of HIV-positive status among people living with HIV in four Sub-Saharan African countries
UR  - http://dx.doi.org/10.1101/2020.09.16.20196105
UR  - http://hdl.handle.net/10044/1/84640
ER  -
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