Imperial College London

Dr Michael K.P. Liu

Faculty of MedicineDepartment of Infectious Disease

Research Associate
 
 
 
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Contact

 

+44 (0)20 3315 5986michael.liu Website

 
 
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Location

 

I.02. 03Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Selected Publications

Song H., Hora B., Bhattacharya T., Goonetilleke N., Liu M.K., et al., (2014) Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus. PLoS One, 9, e102734.

Liu M.K.P., Hawkins H., Ritchie A.J., Ganusov V.V., Whale V., et al., (2013) Vertical T cell immunodominance and epitope entropy determine rate of HIV-1 escape. J. Clin. Invest., 123, 380-93.

Ganusov V.V., Goonetilleke N., Liu M.K.P., Ferrari G., Shaw G.M., et al., (2011) Fitness Costs and Diversity of the Cytotoxic T Lymphocyte (CTL) Response Determine the Rate of CTL Escape during Acute and Chronic Phases of HIV Infection. J. Virol. 85, 10518-28.

Ferrari G.*, Korber B.T.*, Goonetilleke N., Liu M.K., Turnbull E., et al., (2011) Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. PLOS Pathog 7, e1001273.

Goonetilleke N.*, Liu M.K.*, Salazar-Gonzalez J.F.*, Ferrari G., Giorgi E., et al., (2009) The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med. 206, 1253-72. *Equal contribution.

MacLennan C.A, Liu M.K., White S.A., van Oosterhout J.J., Simukonda F., et al., (2007) Diagnostic accuracy and clinical utility of a simplified low cost method of counting CD4 cells with flow cytometry in Malawi: diagnostic accuracy study. BMJ 335, 190-4.

Manzotti C.N., Liu M.K., Burke F., Sant T.A., Dussably L., et al., (2006) Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86. Eur. J. Immunol. 36, 1413-22.