Imperial College London
Professor Michael Way

ProfessorMichaelWay

Faculty of Medicine, Department of Infectious Disease

Professor of Virology
 
 
 
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Contact

 

+44 (0)20 3796 2068michael.way1 Website

 
 
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Location

 

Francis Crick InstituteThe Francis Crick Institute

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Summary

 

Publications

Publication Type
Year
to

223 results found

Moreau V, Way M, 1999, <i>In vitro</i> approaches to study actin and microtubule dependent cell processes, CURRENT OPINION IN CELL BIOLOGY, Vol: 11, Pages: 152-158, ISSN: 0955-0674

Journal article

Machesky LM, Way M, 1998, Cell motility - Actin branches out, NATURE, Vol: 394, Pages: 125-126, ISSN: 0028-0836

Journal article

Sanderson CM, Frischknecht F, Way M, Hollinshead M, Smith GLet al., 1998, Roles of vaccinia virus EEV-specific proteins in intracellular actin tail formation and low pH-induced cell-cell fusion, JOURNAL OF GENERAL VIROLOGY, Vol: 79, Pages: 1415-1425, ISSN: 0022-1317

Journal article

Moreau V, Way M, 1998, Cdc42 is required for membrane dependent actin polymerization in vitro, FEBS LETTERS, Vol: 427, Pages: 353-356, ISSN: 0014-5793

Journal article

McGough A, Chiu W, Way M, 1998, Determination of the gelsolin binding site on F-actin: Implications for severing and capping, BIOPHYSICAL JOURNAL, Vol: 74, Pages: 764-772, ISSN: 0006-3495

Journal article

Sanderson CM, Way M, Smith GL, 1998, Virus-induced cell motility, JOURNAL OF VIROLOGY, Vol: 72, Pages: 1235-1243, ISSN: 0022-538X

Journal article

Way M, 1998, Interaction of vaccinia virus with the actin cytoskeleton, 1st International Minisymposium on Cellular Microbiology - Cell Biology and Signalization in Host-Pathogen Interactions, Publisher: SPRINGER, Pages: 305-310, ISSN: 0015-5632

Conference paper

Higley S, Way M, 1997, Characterization of the vaccinia virus F8L protein, JOURNAL OF GENERAL VIROLOGY, Vol: 78, Pages: 2633-2637, ISSN: 0022-1317

Journal article

Reckmann I, Higley S, Way M, 1997, The vaccinia virus F17R protein interacts with actin, FEBS LETTERS, Vol: 409, Pages: 141-146, ISSN: 0014-5793

Journal article

Higley S, Way M, 1997, Actin and cell pathogenesis, CURRENT OPINION IN CELL BIOLOGY, Vol: 9, Pages: 62-69, ISSN: 0955-0674

Journal article

Parton RG, Way M, Zorzi N, Stang Eet al., 1997, Caveolin-3 associates with developing T-tubules during muscle differentiation, JOURNAL OF CELL BIOLOGY, Vol: 136, Pages: 137-154, ISSN: 0021-9525

Journal article

Cudmore S, Reckmann I, Griffiths G, Way Met al., 1996, Vaccinia virus: A model system for actin-membrane interactions, JOURNAL OF CELL SCIENCE, Vol: 109, Pages: 1739-1747, ISSN: 0021-9533

Journal article

Allen PG, Laham LE, Way M, Janmey PAet al., 1996, Binding of phosphate, aluminum fluoride, or beryllium fluoride to F-actin inhibits severing by gelsolin, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 271, Pages: 4665-4670, ISSN: 0021-9258

Journal article

Sanders MC, Way M, Sakai J, Matsudaira Pet al., 1996, Characterization of the actin cross-linking properties of the scruin-calmodulin complex from the acrosomal process of Limulus sperm, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 271, Pages: 2651-2657, ISSN: 0021-9258

Journal article

Way M, Parton RG, 1996, M-caveolin, a muscle specific caveolin-related protein (vol 376, pg 108, 1995), FEBS LETTERS, Vol: 378, Pages: 101-106, ISSN: 1873-3468

Journal article

Way M, Parton RG, 1996, Erratum: M-caveolin, a muscle specific caveolin-related protein (FEBS Letters 376 (1995) (108-112)), FEBS Letters, Vol: 378, Pages: 101-112, ISSN: 0014-5793

Journal article

CUDMORE S, COSSART P, GRIFFITHS G, WAY Met al., 1995, ACTIN-BASED MOTILITY OF VACCINIA VIRUS, NATURE, Vol: 378, Pages: 636-638, ISSN: 0028-0836

Journal article

WAY M, PARTON RG, 1995, M-CAVEOLIN, A MUSCLE-SPECIFIC CAVEOLIN-RELATED PROTEIN, FEBS LETTERS, Vol: 376, Pages: 108-112, ISSN: 1873-3468

Journal article

LAHAM LE, WAY M, YIN HL, JANMEY PAet al., 1995, IDENTIFICATION OF 2 SITES IN GELSOLIN WITH DIFFERENT SENSITIVITIES TO ADENINE-NUCLEOTIDES, EUROPEAN JOURNAL OF BIOCHEMISTRY, Vol: 234, Pages: 1-7, ISSN: 0014-2956

Journal article

WAY M, SANDERS M, CHAFEL M, TU YH, KNIGHT A, MATSUDAIRA Pet al., 1995, BETA-SCRUIN, A HOMOLOG OF THE ACTIN CROSS-LINKING PROTEIN SCRUIN, IS LOCALIZED TO THE ACROSOMAL VESICLE OF LIMULUS SPERM, JOURNAL OF CELL SCIENCE, Vol: 108, Pages: 3155-3162, ISSN: 0021-9533

Journal article

Way M, Sanders M, Chafel M, Tu YH, Knight A, Matsudaira Pet al., 1995, beta-Scruin, a homologue of the actin crosslinking protein scruin, is localized to the acrosomal vesicle of Limulus sperm., J Cell Sci, Vol: 108 ( Pt 10), Pages: 3155-3162, ISSN: 0021-9533

Scruin (alpha-scruin) is an actin bundling protein found in the acrosomal process of Limulus polyhemus sperm. We have cloned and sequenced a second scruin isoform from Limulus, beta-scruin, that is 67% identical to alpha-scruin. Northern and Southern analyses confirm that beta-scruin and alpha-scruin are encoded by distinct genes. The sequence of beta-scruin, like alpha-scruin, is organized into N- and C-terminal superbarrel domains that are characterized by a six-fold repeat of a 50 residue motif. Western analysis using rabbit polyclonal antisera specific for alpha- and beta-scruin indicate that beta-scruin, like alpha-scruin, is found in Limulus sperm but not blood or muscle. Both immunofluorescence microscopy and immunogold-EM localize beta-scruin within the acrosomal vesicle at the anterior of sperm but not in the acrosomal process. The function of beta-scruin in this membrane-bounded compartment that is devoid of actin is unknown. However, the location of beta-scruin together with the fact that it contains two putative beta-superbarrel structural folds, which are known to be catalytic domains in a number of proteins, suggests it may have a possible enzymatic role.

Journal article

MCGOUGH A, WAY M, 1995, MOLECULAR-MODEL OF AN ACTIN FILAMENT CAPPED BY A SEVERING PROTEIN, Workshop on Molecular Imaging of Cytoskeletal Protein Assembly, Publisher: ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Pages: 144-150, ISSN: 1047-8477

Conference paper

WAY M, SANDERS M, GARCIA C, SAKAI J, MATSUDAIRA Pet al., 1995, SEQUENCE AND DOMAIN ORGANIZATION OF SCRUIN, AN ACTIN CROSS-LINKING PROTEIN IN THE ACROSOMAL PROCESS OF LIMULUS SPERM, JOURNAL OF CELL BIOLOGY, Vol: 128, Pages: 51-60, ISSN: 0021-9525

Journal article

MCGOUGH A, WAY M, DEROSIER D, 1994, DETERMINATION OF THE ALPHA-ACTININ-BINDING SITE ON ACTIN-FILAMENTS BY CRYOELECTRON MICROSCOPY AND IMAGE-ANALYSIS, JOURNAL OF CELL BIOLOGY, Vol: 126, Pages: 433-443, ISSN: 0021-9525

Journal article

ALMO SC, POLLARD TD, WAY M, LATTMAN EEet al., 1994, PURIFICATION, CHARACTERIZATION AND CRYSTALLIZATION OF ACANTHAMOEBA PROFILIN EXPRESSED IN ESCHERICHIA-COLI, JOURNAL OF MOLECULAR BIOLOGY, Vol: 236, Pages: 950-952, ISSN: 0022-2836

Journal article

KAHANA E, MARSH PJ, HENRY AJ, WAY M, GRATZER WBet al., 1994, CONFORMATION AND PHASING OF DYSTROPHIN STRUCTURAL REPEATS, JOURNAL OF MOLECULAR BIOLOGY, Vol: 235, Pages: 1271-1277, ISSN: 0022-2836

Journal article

POPE B, WAY M, MATSUDAIRA PT, WEEDS Aet al., 1994, CHARACTERIZATION OF THE F-ACTIN BINDING DOMAINS OF VILLIN - CLASSIFICATION OF F-ACTIN BINDING-PROTEINS INTO 2 GROUPS ACCORDING TO THEIR BINDING-SITES ON ACTIN, FEBS LETTERS, Vol: 338, Pages: 58-62, ISSN: 0014-5793

Journal article

WAY M, MATSUDAIRA P, 1993, THE SECRETS OF SEVERING, CURRENT BIOLOGY, Vol: 3, Pages: 887-890, ISSN: 0960-9822

Journal article

WAY M, POPE B, WEEDS AG, 1992, EVIDENCE FOR FUNCTIONAL HOMOLOGY IN THE F-ACTIN BINDING DOMAINS OF GELSOLIN AND ALPHA-ACTININ - IMPLICATIONS FOR THE REQUIREMENTS OF SEVERING AND CAPPING, JOURNAL OF CELL BIOLOGY, Vol: 119, Pages: 835-842, ISSN: 0021-9525

Journal article

MANNHERZ HG, GOOCH J, WAY M, WEEDS AG, MCLAUGHLIN PJet al., 1992, CRYSTALLIZATION OF THE COMPLEX OF ACTIN WITH GELSOLIN SEGMENT-1, JOURNAL OF MOLECULAR BIOLOGY, Vol: 226, Pages: 899-901, ISSN: 0022-2836

Journal article

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