Publications
151 results found
Bromage DI, AJones D, Rathod KS, et al., 2013, OUTCOME OF 1051 OCTOGENARIANS AFTER PRIMARY PERCUTANEOUS CORONARY INTERVENTION FOR ST ELEVATION MYOCARDIAL INFARCTION: OBSERVATIONAL COHORT FROM THE LONDON HEART ATTACK GROUP, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: BMJ PUBLISHING GROUP, Pages: A27-U84, ISSN: 1355-6037
Akhtar MM, Jones DA, Rathod KS, et al., 2013, CORONARY ARTERY BYPASS GRAFT PATIENTS TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION HAVE HIGH LONG-TERM ADVERSE EVENT RATES (10 920 STEMI PATIENTS FROM THE LONDON HEART ATTACK GROUP), Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: BMJ PUBLISHING GROUP, Pages: A30-A30, ISSN: 1355-6037
Kelly DJ, McCann GP, Blackman D, et al., 2013, Complete Versus culprit-Lesion only PRirnary PCI Trial (CVLPRIT): a multicentre trial testing management strategies when multivessel disease is detected at the time of primary PCI: rationale and design, EUROINTERVENTION, Vol: 8, Pages: 1190-1198, ISSN: 1774-024X
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- Citations: 35
Ali O, Schultz C, Jabbour A, et al., 2012, Catheter Laboratory Predictors Of Post Procedure Paraprosthetic Aortic Regurgitation Following Self-expanding Medtronic CoreValve Implantation: A Multicentre Registry Analysis, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B263-B263, ISSN: 0735-1097
Tarkin JM, Kelion A, Mittal T, et al., 2012, CASE REPORT Exertional dyspnoea and syncope, BRITISH MEDICAL JOURNAL, Vol: 344, ISSN: 0959-535X
Dubrey SW, Pearse S, Dahdal M, et al., 2011, Two cases of massive mitral annular calcification mimicking left atrial neoplasms., BMJ Case Rep, Vol: 2011
The authors describe two cases of massive mitral annular calcification, initially picked up on echocardiography and suspected of being neoplastic. Subsequent evaluation by CT scanning confirmed the location, aetiology, structure and diagnosis. Both cases demonstrated large masses, with calcification of varying density. This is likely explained by the presence of the previously reported amorphous caseous material demonstrated to be present within such mass structures. Such a feature is described as caseous degeneration. Both patients described have been managed conservatively with medical therapy, predominantly due to their age and general frailty.
Balerdi M, Ellis DY, Grieve P, et al., 2011, Aeromedical transfer to reduce delay in primary angioplasty, RESUSCITATION, Vol: 82, Pages: 947-950, ISSN: 0300-9572
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- Citations: 5
Spiro JR, Digby JE, Ghimire G, et al., 2011, Brachial artery low-flow-mediated constriction is increased early after coronary intervention and reduces during recovery after acute coronary syndrome: characterization of a recently described index of vascular function, EUROPEAN HEART JOURNAL, Vol: 32, Pages: 856-866, ISSN: 0195-668X
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- Citations: 41
Al-Housni MB, Hutchings F, Dalby M, et al., 2009, Does myocardial perfusion scintigraphy predict improvement in symptoms and exercise capacity following successful elective percutaneous coronary intervention?, JOURNAL OF NUCLEAR CARDIOLOGY, Vol: 16, Pages: 869-877, ISSN: 1071-3581
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- Citations: 6
Spiro J, Ghimire G, Mason M, et al., 2009, CHARACTERISATION OF SYSTEMIC VASCULAR PHENOTYPE USING LOW-FLOW MEDIATED VASOCONSTRICTION IN PATIENTS WITH UNDERGOING CORONARY INTERVENTION, 14th Annual Meeting of the European-Council-for-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 1172-1172, ISSN: 0194-911X
Spiro J, Digby J, Ghimire G, et al., 2009, MEASURING THE CHEMOTAXIS RESPONSE OF PERIPHERAL MONONUCLEAR CELLS IN HUMANS: VALIDATION AND INVESTIGATION IN PERCUTANEOUS CORONARY INTERVENTION, 14th Annual Meeting of the European-Council-for-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 1173-1173, ISSN: 0194-911X
Dalby M, Kharbanda R, Ghimire G, et al., 2009, Achieving routine sub 30 minute door-to-balloon times in a high volume 24/7 primary angioplasty center with autonomous ambulance diagnosis and immediate catheter laboratory access, AMERICAN HEART JOURNAL, Vol: 158, Pages: 829-835, ISSN: 0002-8703
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- Citations: 7
Tanigawa J, Barlis P, Dimopoulos K, et al., 2009, The influence of strut thickness and cell design on immediate apposition of drug-eluting stents assessed by optical coherence tomography, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 134, Pages: 180-188, ISSN: 0167-5273
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- Citations: 114
Moore P, Barlis P, Spiro J, et al., 2009, A Randomized Optical Coherence Tomography Study of Coronary Stent Strut Coverage and Luminal Protrusion With Rapamycin-Eluting Stents, Journal of the American College of Cardiology Cardiovascular Interventions, Vol: 2, Pages: 437-444, ISSN: 1936-8798
Objectives We used optical coherence tomography, which has a resolution of <20 mu m, to analyze thin layers of neointima in rapamycin-eluting coronary stents.Background Lack of neointimal coverage has been implicated in the pathogenesis of drug-eluting coronary stent thrombosis. Angiography and intracoronary ultrasound lack the resolution to examine this.Methods We conducted a randomized trial in patients receiving polymer-coated rapamycin-eluting stents (Cypher, Cordis, Johnson & Johnson, Miami, Florida) and nonpolymer rapamycin-eluting stents (Yukon, Translumina, Hechingen, Germany) to examine neointimal thickness, stent strut coverage, and protrusion at 90 days. Twenty-four patients (n = 12 for each group) underwent stent deployment and invasive follow-up at 90 days with optical coherence tomography. The primary end point was binary stent strut coverage. Coprimary end points were neointimal thickness and stent strut luminal protrusion.Results No patient had angiographic restenosis. For polymer-coated and nonpolymer rapamycin-eluting stents, respectively, mean (SD), neointimal thickness was 77.2 (25.6) mu m versus 191.2 (86.7) mu m (p < 0.001). Binary stent strut coverage was 88.3% (11.8) versus 97.2% (6.1) (p = 0.030). Binary stent strut protrusion was 26.5% (17.5) versus 4.8% (8.6) (p = 0.001).Conclusions Mean neointimal thickness for the polymer-coated rapamycin-eluting stent was significantly less than the nonpolymer rapamycin-eluting stent but as a result coverage was not homogenous, with >10% of struts being uncovered. High-resolution imaging allowed development of the concept of the protrusion index, and >25% of struts protruded into the vessel lumen with the polymer-coated rapamycin-eluting stent compared with <5% with the nonpolymer rapamycin-eluting stent. These findings may have important implications for the risk of stent thrombosis and, therefore, future stent design. (An optical coherence tomography study to determine stent coverag
Barlis P, Gonzalo N, Di Mario C, et al., 2009, A multicentre evaluation of the safety of intracoronary optical coherence tomography, EUROINTERVENTION, Vol: 5, Pages: 90-95, ISSN: 1774-024X
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- Citations: 62
Lindsay AC, Mahesh B, Gaer JA, et al., 2009, Ruptured sinus of Valsalva aneurysm presenting as ST-elevation myocardial infarction, NATURE REVIEWS CARDIOLOGY, Vol: 6, Pages: 379-382, ISSN: 1759-5002
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- Citations: 2
Ghimire G, McCormack A, Spiro J, et al., 2009, Endothelial Cell Injury Induced by Intracoronary Sera in Patients With ST Elevation Myocardial Infarction, 58th Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: A312-A312, ISSN: 0735-1097
Asgar AW, Mullen MJ, Delahunty N, et al., 2009, Transcatheter aortic valve intervention through the axillary artery for the treatment of severe aortic stenosis, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol: 137, Pages: 773-775, ISSN: 0022-5223
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- Citations: 32
Ghimire G, Spiro J, Kharbanda R, et al., 2009, Initial evidence for the return of coronary vasoreactivity following the absorption of bioabsorbable magnesium alloy coronary stents, EUROINTERVENTION, Vol: 4, Pages: 481-484, ISSN: 1774-024X
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- Citations: 49
Ghimire G, Smith J, Spiro J, et al., 2008, Reactive Immunoglobullin M At the Site Of Coronary Occlusion In Patients With St Elevation Myocardial Infarction, 81st Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S582-S582, ISSN: 0009-7322
Westbrook JA, Polden J, Leong H, et al., 2008, Problem of resistance to thrombolytic therapy after acute myocardial infarction: A proteomic approach, HEART, Vol: 94, ISSN: 1355-6037
Spiro J, Dalby M, Ghimire G, et al., 2008, Primary coronary intervention for acute myocardial infarction affords time dependant mortality benefits, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 568-568, ISSN: 0195-668X
Ghimire G, Spiro J, Kharbanda R, et al., 2008, Amplified proinflammatory and attenuated immunomodulatory T cells at the culprit site of ST elevation myocardial infarction may contribute to reperfusion injury, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 573-573, ISSN: 0195-668X
Moore PR, Barlis P, Spiro J, et al., 2008, An optical coherence tomography study to determine 90-day coronary stent coverage and luminal protrusion in polymer coated versus polymer free rapamycin-eluting stents, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 147-147, ISSN: 0195-668X
Ghimire G, Spiro J, Kharbanda R, et al., 2008, Coronary artery vasomotion may be possible in segments previously treated with bioabsorbable magnesium alloy coronary stents, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A123-A123, ISSN: 1355-6037
Asgar AW, Delahunty N, Dalby M, et al., 2008, Percutaneous aortic valve replacement in the United Kingdom using the corevalve revalving system, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A8-A8, ISSN: 1355-6037
Ghimire G, Spiro JR, Kharbanda RK, et al., 2007, Evidence for the return of coronary vasoreactivity following absorption of a bioabsorbable magnesium alloy coronary stent, 19th Annual Transcatheter Cardiovascular Therapeutics Symposium, Publisher: EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, Pages: 146L-146L, ISSN: 0002-9149
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- Citations: 1
Dalby MC, Kharbanda RK, Ghimire G, et al., 2007, Re-appraisal of interhospital transfer for primary angioplasty in the context of an effective service with rapid institutional door-balloon times, 80th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 430-430, ISSN: 0009-7322
Tanigawa J, Barlis P, Dimopoulos K, et al., 2007, Strut malapposition in overlapping drug-eluting stents by optical coherence tomography, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 200-201, ISSN: 0195-668X
Dalby M, Kharbanda R, Ghimire G, et al., 2007, Delays in delivering primary angioplasty with interhospital transfer result in limited mortality benefit in real-world practice in the context of a high-quality thrombolysis service, Annual Scientific Conference of the British-Cardiovascular-Society, Publisher: B M J PUBLISHING GROUP, Pages: A5-A5, ISSN: 1355-6037
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