Imperial College London

DrMonicaPirani

Faculty of MedicineSchool of Public Health

Lecturer in Biostatistics
 
 
 
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Contact

 

monica.pirani

 
 
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Location

 

706School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Castellani:2022:10.1016/j.envres.2022.114362,
author = {Castellani, B and Bartington, S and Wistow, J and Heckels, N and Ellison, A and Van, Tongeren M and Arnold, SR and Barbrook-Johnson, P and Bicket, M and Pope, FD and Russ, TC and Clarke, CL and Pirani, M and Schwannauer, M and Vieno, M and Turnbull, R and Gilbert, N and Reis, S},
doi = {10.1016/j.envres.2022.114362},
journal = {Environmental Research},
pages = {1--13},
title = {Mitigating the impact of air pollution on dementia and brain health: Setting the policy agenda},
url = {http://dx.doi.org/10.1016/j.envres.2022.114362},
volume = {215},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundEmerging research suggests exposure to high levels of air pollution at critical points in the life-course is detrimental to brain health, including cognitive decline and dementia. Social determinants play a significant role, including socio-economic deprivation, environmental factors and heightened health and social inequalities. Policies have been proposed more generally, but their benefits for brain health have yet to be fully explored.Objective and methodsOver the course of two years, we worked as a consortium of 20+ academics in a participatory and consensus method to develop the first policy agenda for mitigating air pollution's impact on brain health and dementia, including an umbrella review and engaging 11 stakeholder organisations.ResultsWe identified three policy domains and 14 priority areas. Research and Funding included: (1) embracing a complexities of place approach that (2) highlights vulnerable populations; (3) details the impact of ambient PM2.5 on brain health, including current and historical high-resolution exposure models; (4) emphasises the importance of indoor air pollution; (5) catalogues the multiple pathways to disease for brain health and dementia, including those most at risk; (6) embraces a life course perspective; and (7) radically rethinks funding. Education and Awareness included: (8) making this unrecognised public health issue known; (9) developing educational products; (10) attaching air pollution and brain health to existing strategies and campaigns; and (11) providing publicly available monitoring, assessment and screening tools. Policy Evaluation included: (12) conducting complex systems evaluation; (13) engaging in co-production; and (14) evaluating air quality policies for their brain health benefits.ConclusionGiven the pressing issues of brain health, dementia and air pollution, setting a policy agenda is crucial. Policy needs to be matched by scientific evidence and appropriate guidelines, including bespoke strateg
AU - Castellani,B
AU - Bartington,S
AU - Wistow,J
AU - Heckels,N
AU - Ellison,A
AU - Van,Tongeren M
AU - Arnold,SR
AU - Barbrook-Johnson,P
AU - Bicket,M
AU - Pope,FD
AU - Russ,TC
AU - Clarke,CL
AU - Pirani,M
AU - Schwannauer,M
AU - Vieno,M
AU - Turnbull,R
AU - Gilbert,N
AU - Reis,S
DO - 10.1016/j.envres.2022.114362
EP - 13
PY - 2022///
SN - 0013-9351
SP - 1
TI - Mitigating the impact of air pollution on dementia and brain health: Setting the policy agenda
T2 - Environmental Research
UR - http://dx.doi.org/10.1016/j.envres.2022.114362
UR - https://www.sciencedirect.com/science/article/pii/S0013935122016899?via%3Dihub
UR - http://hdl.handle.net/10044/1/99989
VL - 215
ER -