Imperial College London
Alternate

DrMonicaPirani

Faculty of Medicine, School of Public Health

Lecturer in Biostatistics
 
 
 
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Contact

 

monica.pirani

 
 
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Location

 

706School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Antolini:2006,
author = {Antolini, G and Pirani, M and Morandi, G and Sorio, C},
journal = {Epidemiol Prev},
pages = {91--99},
title = {[Gender difference and mortality in a cohort of heroin users in the Provinces of Modena and Ferrara, 1975-1999].},
url = {https://www.ncbi.nlm.nih.gov/pubmed/16909957},
volume = {30},
year = {2006}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE: To analyse overall and cause-specific hazards of death in a cohort of heroin users, separately by gender, survival and other risk factors. DESIGN AND SETTING: Longitudinal study of intravenous heroin users; subjects were enrolled between 1975 and 1999 in public health services of the Provinces of Modena and Ferrara and were included in a treatment program. MAIN OUTCOME MEASURES: For each gender, age-standardized mortality rates and standardized mortality ratios (SMR) for all causes and for specific causes. Kaplan-Meier method was used for estimating survival probability and Cox regression model to estimate hazard ratios (HR) of death. RESULTS: in the cohort of 4.644 intravenous drug users, 801 deaths were observed. In both sexes, mortality due to AIDS was lower in subjects enrolled in 1990-99 than among those enrolled in 1980-89. Mortality caused by overdose was particularly high in males enrolled between 1995-99. (SMRs in males and females were respectively 12.12 (95% CI 11.22-13.08) and 20.26 (17.23-23.83). Survival probability at 20 years of observation was 62% (60% for males and 68% for females). Risk of death was highest in males, in subjects enrolled after age 25, in subjects with a low educational level and in unemployed persons. CONCLUSION: Gender and socioeconomic conditions are important determinants of mortality among heroin users. The increase in deaths from heroin overdose in subjects enrolled in the recent years requires particular attention.
AU  - Antolini,G
AU  - Pirani,M
AU  - Morandi,G
AU  - Sorio,C
EP  - 99
PY  - 2006///
SN  - 1120-9763
SP  - 91
TI  - [Gender difference and mortality in a cohort of heroin users in the Provinces of Modena and Ferrara, 1975-1999].
T2  - Epidemiol Prev
UR  - https://www.ncbi.nlm.nih.gov/pubmed/16909957
VL  - 30
ER  -
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