Imperial College London
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Dr Monsey McLeod

Faculty of Medicine, Department of Infectious Disease

Honorary Research Fellow
 
 
 
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Contact

 

monsey.mcleod

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Hayhoe:2021:10.1371/journal.pmed.1003737,
author = {Hayhoe, B},
doi = {10.1371/journal.pmed.1003737},
journal = {PLoS Medicine},
pages = {1--20},
title = {Public preferences for delayed or immediate antibiotic prescriptions in UK primary care: a choice experiment},
url = {http://dx.doi.org/10.1371/journal.pmed.1003737},
volume = {18},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Delayed (or ‘back-up’) antibiotic prescription, where the patient is given a prescription but advised todelay initiating antibiotics, has been shown to be effective in reducing antibiotic use in primary care.However, this strategy is not widely used in the UK. This study aimed to identify factors influencingpreferences among the UK public for delayed prescription, and understand their relative importance,to help increase appropriate use of this prescribing option.Methods and FindingsWe conducted an online choice experiment in two UK general population samples: adults, and parentsof children under 18 years. Respondents were presented with twelve scenarios in which they, or theirchild, might need antibiotics for a respiratory tract infection, and asked to choose either an immediateor a delayed prescription. Scenarios were described by seven attributes. Data were collected betweenNovember 2018 and February 2019. Respondent preferences were modelled using mixed-effectslogistic regression.The survey was completed by 802 adults and 801 parents (75% of those who opened the survey). Thesamples reflected the UK population in age, sex, ethnicity and country of residence. The mostimportant determinant of respondent choice was symptom severity, especially for cough-relatedsymptoms. In the adult sample the probability of choosing delayed prescription was 0.53 (95% CI 0.50-0.56, p<.001) for a chesty cough and runny nose, compared to 0.30 (0.28-0.33, p<.001) for a chestycough with fever, 0.47 (0.44-0.50, p<.001) for sore throat with swollen glands and 0.37 (0.34-0.39,p<.001) for sore throat, swollen glands and fever. Respondents were less likely to choose delayedprescription with increasing duration of illness (odds ratio 0.94 (0.92-0.96, p<0.001)). Probabilities ofchoosing delayed prescription were similar for parents considering treatment for a child (44% ofchoices vs. 42% for adults, p=0.04). However, parents differed from the adult sample in showing
AU  - Hayhoe,B
DO  - 10.1371/journal.pmed.1003737
EP  - 20
PY  - 2021///
SN  - 1549-1277
SP  - 1
TI  - Public preferences for delayed or immediate antibiotic prescriptions in UK primary care: a choice experiment
T2  - PLoS Medicine
UR  - http://dx.doi.org/10.1371/journal.pmed.1003737
UR  - https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003737
UR  - http://hdl.handle.net/10044/1/91272
VL  - 18
ER  -
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