Imperial College London

ProfessorNeilAlford

Central FacultyOffice of the Provost

Associate Provost (Academic Planning)
 
 
 
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Contact

 

+44 (0)20 7594 6724n.alford

 
 
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Assistant

 

Miss Catherine Graham +44 (0)20 7594 3330

 
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Location

 

2..05 (in RSM) or 3.09 (in the Faculty Building)Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Xie:2013:10.1007/s12274-013-0327-5,
author = {Xie, F and Pang, J and Centeno, A and Ryan, M and Riley, J and Alford, N},
doi = {10.1007/s12274-013-0327-5},
journal = {Nano Research},
pages = {495--510},
title = {Nanoscale control of Ag nanostructures for plasmonic fluorescence enhancement of near-infrared dyes},
url = {http://dx.doi.org/10.1007/s12274-013-0327-5},
volume = {6},
year = {2013}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Potential utilization of proteins for early detection and diagnosis of various diseases has drawn considerable interest in the development of protein-based detection techniques. Metal induced fluorescence enhancement offers the possibility of increasing the sensitivity of protein detection in clinical applications. We report the use of tunable plasmonic silver nanostructures for the fluorescence enhancement of a near-infrared (NIR) dye (Alexa Fluor 790). Extensive fluorescence enhancement of ∼2 orders of magnitude is obtained by the nanoscale control of the Ag nanostructure dimensions and interparticle distance. These Ag nanostructures also enhanced fluorescence from a dye with very high quantum yield (7.8 fold for Alexa Fluor 488, quantum efficiency (Qy) = 0.92). A combination of greatly enhanced excitation and an increased radiative decay rate, leading to an associated enhancement of the quantum efficiency leads to the large enhancement. These results show the potential of Ag nanostructures as metal induced fluorescence enhancement (MIFE) substrates for dyes in the NIR “biological window” as well as the visible region. Ag nanostructured arrays fabricated by colloidal lithography thus show great potential for NIR dye-based biosensing applications.
AU - Xie,F
AU - Pang,J
AU - Centeno,A
AU - Ryan,M
AU - Riley,J
AU - Alford,N
DO - 10.1007/s12274-013-0327-5
EP - 510
PY - 2013///
SN - 1998-0124
SP - 495
TI - Nanoscale control of Ag nanostructures for plasmonic fluorescence enhancement of near-infrared dyes
T2 - Nano Research
UR - http://dx.doi.org/10.1007/s12274-013-0327-5
UR - http://hdl.handle.net/10044/1/13829
VL - 6
ER -