Imperial College London

Dr Nair Bonito

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Honorary Research Associate



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Institute of Reproductive and Developmental BiologyHammersmith Campus





Nair Bonito received her PhD in Molecular Biology from Imperial College London. During her PhD, she studied the regulation of IL-6 type cytokine responses by MAPKs. Specializing in cell lines and different molecular biology techniques including ChIP and flow cytometry, Nair showed that the protein ERK2 binds to gp130 promoter, regulating its expression and, consequently, its signalling (Bonito, et al 2014). In 2013, she joined the Epigenetics Unit in the Division of Cancer with Prof Bob Brown. Currently, she is working on the mechanisms though which certain biomarkers affect ovarian cancer progression and chemo resistance.

Selected Publications

Journal Articles

Bonito NA, Borley J, Wilhelm-Benartzi CS, et al., 2016, Epigenetic Regulation of the Homeobox Gene MSX1 Associates with Platinum-Resistant Disease in High-Grade Serous Epithelial Ovarian Cancer., Clinical Cancer Research, Vol:22, ISSN:1557-3265, Pages:3097-3104

Bonito NA, Drechsler J, Stoecker S, et al., 2014, Control of gp130 expression by the mitogen-activated protein kinase ERK2, Oncogene, Vol:33, ISSN:0950-9232, Pages:2255-2263

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